Evidence map›Paper›PMID 26907340›Full record

ArticleNutrients2016

A Comprehensive Analysis of Body Mass Index Effect on in Vitro Fertilization Outcomes.

Veronica Sarais, Luca Pagliardini, Giorgia Rebonato, Enrico Papaleo, Massimo Candiani, Paola Viganò

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 62 citations in OpenAlex.

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  15. Lipid Metabolism Was Associated With OocyteFrontiers in cell and developmental biology · 2021
    Article
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  19. Maternal body mass index affects embryo morphokinetics: a time-lapse study.Journal of assisted reproduction and genetics · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Veronica SaraisObstetrics and Gynecology Unit, San Raffaele Scientific Institute, 20132 Milano, Italy. sarais.veronica@hsr.it.
Luca PagliardiniDivision of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy. pagliardini.luca@hsr.it.
Giorgia RebonatoObstetrics and Gynecology Unit, San Raffaele Scientific Institute, 20132 Milano, Italy. g.rebonato@studenti.unisr.it.
Enrico PapaleoObstetrics and Gynecology Unit, San Raffaele Scientific Institute, 20132 Milano, Italy. papleo.enrico@hsr.it.
Massimo CandianiObstetrics and Gynecology Unit, San Raffaele Scientific Institute, 20132 Milano, Italy. candiani.massimo@hsr.it.
Paola ViganòDivision of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy. vigano.paola@hsr.it.
San Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of a raised body mass index (BMI) on the outcome of assisted reproduction technology (ART) still represents a controversial issue. Even less clear is whether BMI acts with a potential detrimental effect on IVF outcomes via a deleterious effect on innate quality of oocytes or on the environmental milieu within the uterus. With the aim to better understand the mechanisms underlying the potential deleterious effect of an increased BMI on IVF outcomes, we have evaluated the effects of female BMI on number and quality of retrieved oocytes, fertilization rate, embryo score and incidences of ongoing pregnancy and live births among couples undergoing IVF in an Italian population. Data from 1602 women who underwent their first IVF cycle were retrospectively analyzed. A significantly reduced percentage of mature oocytes when comparing obese (BMI ≥ 30 kg/m²) and normal-weight patients (BMI = 18.50-24.99 kg/m²) was found. After adjusting for maternal age and other confounders, odds for ongoing pregnancy rate showed no differences across different BMI categories. However, a significant increased odds ratio (OR) could be observed for miscarriage rate in patients with BMI ≥ 25 (OR = 2.5; p = 0.04). These results should be taken into account in order to define optimal strategies for overweight and obese patients referring to ART procedures.

Indexed as

Body Mass IndexFertilization in VitroAbortion, SpontaneousAdultChi-Square DistributionFemaleHumansItalyLive BirthLogistic ModelsMiddle AgedObesityOdds RatioOocyte RetrievalPregnancyPregnancy Rateassisted reproductionBMIinfertilityoocyte

Identifiers

PMID26907340
PMCPMC4808839
OpenAlexW2284884853

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.