ArticleMolecules (Basel, Switzerland)2016
Catechin Hydrate Augments the Antibacterial Action of Selected Antibiotics against Staphylococcus aureus Clinical Strains.
Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
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- Phytotherapeutic potential against MRSA: mechanisms, synergy, and therapeutic prospects.Chinese medicine · 2024Article
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- Sensitivity of Staphylococcal Biofilm to Selected Compounds of Plant Origin.Antibiotics (Basel, Switzerland) · 2021Review
- Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases.Environmental science and pollution research international · 2021Article
- Sub-Inhibitory Concentrations of Ciprofloxacin Alone and Combinations with Plant-Derived Compounds againstAntibiotics (Basel, Switzerland) · 2021Article
- Protein targets in red complex pathogens for catechin.Bioinformation · 2021Article
- Role of symbiosis in the discovery of novel antibiotics.The Journal of antibiotics · 2020Review
- Phytochemical Profile and Biological Activities of Tendrils and Leaves Extracts from a Variety ofAntioxidants (Basel, Switzerland) · 2020Article
- Phenolic Compounds Diminish Antibiotic Resistance ofInternational journal of environmental research and public health · 2018Review
- Effects of Blue-Light-Induced Free Radical Formation from Catechin Hydrate on the Inactivation ofMolecules (Basel, Switzerland) · 2018Article
- Antimicrobial Potential of Caffeic Acid againstBioMed research international · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synergistic effects between commonly used antibiotics and natural substances may be an alternative to conventional antibacterial therapies. The objective of the presented study was to assess the in vitro antibacterial activity of catechin hydrate (CH) and evaluate the interactions of CH with selected antibiotics using Staphylococcus aureus clinical and reference strains. CH displayed diverse activity towards examined S. aureus strains, with minimal inhibitory concentrations (MICs) ranging from 256 to 2048 µg/mL. The interaction between CH and antibiotics was assessed by an E-test. The most significant synergistic effects were noticed for CH in combination with clindamycin and erythromycin. For cefoxitin and vancomycin a decrease of MIC values in the presence of CH was also observed, but it did not reach statistical significance. The obtained results demonstrate that CH shows antimicrobial activity against Staphylococcus aureus clinical strains. What is more, we proved a synergistic effect of CH with erythromycin and clindamycin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.