ArticleDevelopmental cell2016
The Specification of Geometric Edges by a Plant Rab GTPase Is an Essential Cell-Patterning Principle During Organogenesis in Arabidopsis.
Article in Developmental cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 80 citations in OpenAlex.
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- The role of geometry in morphogenesis.Development (Cambridge, England) · 2026Review
- Regulatory Pathways of the Maturation-Related Decline in Adventitious Root Formation in Forest Tree Species.Plants (Basel, Switzerland) · 2026Review
- A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis.The EMBO journal · 2026Article
- The arabidopsis WAVE/SCAR protein BRICK1 associates with cell edges and plasmodesmata.PloS one · 2025Article
- Recruitment of Cdc48 to chloroplasts by a UBX-domain protein in chloroplast-associated protein degradation.Nature plants · 2024Article
- A self-regulatory cell-wall-sensing module at cell edges controls plant growth.Nature plants · 2024Article
- On the edge - how plant cells monitor growth.Nature plants · 2024Article
- Emerging role of small GTPases and their interactome in plants to combat abiotic and biotic stress.Protoplasma · 2023Review
- An actin remodeling role for Arabidopsis processing bodies revealed by their proximity interactome.The EMBO journal · 2023Article
- Article
- Rab GTPases, tethers, and SNAREs work together to regulateFrontiers in plant science · 2023Review
- RAB GTPases and SNAREs at the trans-Golgi network in plants.Journal of plant research · 2022Review
- Screening of Differentially Expressed Genes and Localization Analysis of Female Gametophyte at the Free Nuclear Mitosis Stage inInternational journal of molecular sciences · 2022Article
- Fifteen compelling open questions in plant cell biology.The Plant cell · 2022Review
- Cell biology of primary cell wall synthesis in plants.The Plant cell · 2022Review
- The role of pectin phase separation in plant cell wall assembly and growth.Cell surface (Amsterdam, Netherlands) · 2021Review
- Multiple functions of the vacuole in plant growth and fruit quality.Molecular horticulture · 2021Review
- Microtubule associated protein WAVE DAMPENED2-LIKE (WDL) controls microtubule bundling and the stability of the site of tip-growth in Marchantia polymorpha rhizoids.PLoS genetics · 2021Article
- The AGCVIII kinase Dw2 modulates cell proliferation, endomembrane trafficking, and MLG/xylan cell wall localization in elongating stem internodes of Sorghum bicolor.The Plant journal : for cell and molecular biology · 2021Article
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Plant organogenesis requires control over division planes and anisotropic cell wall growth, which each require spatial patterning of cells. Polyhedral plant cells can display complex patterning in which individual faces are established as biochemically distinct domains by endomembrane trafficking. We now show that, during organogenesis, the Arabidopsis endomembrane system specifies an important additional cellular spatial domain: the geometric edges. Previously unidentified membrane vesicles lying immediately beneath the plasma membrane at cell edges were revealed through localization of RAB-A5c, a plant GTPase of the Rab family of membrane-trafficking regulators. Specific inhibition of RAB-A5c activity grossly perturbed cell geometry in developing lateral organs by interfering independently with growth anisotropy and cytokinesis without disrupting default membrane trafficking. The initial loss of normal cell geometry can be explained by a failure to maintain wall stiffness specifically at geometric edges. RAB-A5c thus meets a requirement to specify this cellular spatial domain during organogenesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.