Evidence map›Paper›PMID 26906720›Full record

ReviewInternational immunopharmacology2016

Tissue-resident dendritic cells and diseases involving dendritic cell malfunction.

Keqiang Chen, Ji Ming Wang, Ruoxi Yuan, Xiang Yi, Liangzhu Li, Wanghua Gong, Tianshu Yang, Liwu Li, Shaobo Su

Open access · greenAbstract readReview
In one paragraph

Review in International immunopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Sjögren's Syndrome Treatments in the Microbiome Era.Advances in geriatric medicine and research · 2023
    Article
  12. Distribution and maturation state of peripheral blood dendritic cells in children with primary hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  13. Article
  14. Testing Antigens, Antibodies, and Immune Cells in COVID-19 as a Public Health Topic-Experience and Outlines.International journal of environmental research and public health · 2021
    Review
  15. Review
  16. Review
  17. Article
  18. Neurogenic tachykinin mechanisms in experimental nephritis of rats.Pflugers Archiv : European journal of physiology · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Keqiang ChenShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA; Laboratory of Inflammation Biology, Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0910, USA. Electronic address: keqiangc8@gmail.com.
Ji Ming WangCancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA. Electronic address: wangji@mail.nih.gov.
Ruoxi YuanLaboratory of Inflammation Biology, Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0910, USA.
Xiang YiCancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA.
Liangzhu LiCancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA.
Wanghua GongCancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA; Basic Research Program, Leidos Biomedical Research, Inc., Frederick, MD 21702, USA.
Tianshu YangShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Liwu LiLaboratory of Inflammation Biology, Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0910, USA.
Shaobo SuShanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Center for Cancer Research · USNational Cancer Institute · USVirginia Tech · USLeidos Biomedical Research Inc. (United States)Shanghai Tenth People's Hospital · CNTongji University · CN

Funding

The Role of Cellular Receptors Involved in Inflammation and Tumor ProgressionZIABC010015 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, JI MING · 2009 to 2023
$6.3M
Role of Formylpeptide Receptors in Host DefenseZIABC010725 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, JI MING · 2009 to 2023
$6.3M
The Role of Cellular Receptors Involved in Inflammation and Tumor ProgressionZ01BC010015 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, JI MING · 1996 to 2008
$944k
CCR NIH HHS HHSN261200800001CIntramural NIH HHS Z01 BC010015NCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

Dendritic cells (DCs) control immune responses and are central to the development of immune memory and tolerance. DCs initiate and orchestrate immune responses in a manner that depends on signals they receive from microbes and cellular environment. Although DCs consist mainly of bone marrow-derived and resident populations, a third tissue-derived population resides the spleen and lymph nodes (LNs), different subsets of tissue-derived DCs have been identified in the blood, spleen, lymph nodes, skin, lung, liver, gut and kidney to maintain the tolerance and control immune responses. Tissue-resident DCs express different receptors for microbe-associated molecular patterns (MAMPs) and damage-associated molecular patterns (DAMPs), which were activated to promote the production of pro- or anti-inflammatory cytokines. Malfunction of DCs contributes to diseases such as autoimmunity, allergy, and cancer. It is therefore important to update the knowledge about resident DC subsets and diseases associated with DC malfunction.

Indexed as

AnimalsAutoimmune DiseasesCytokinesDendritic CellsHumansHypersensitivityImmune ToleranceImmunologic MemoryImmunotherapyInflammation MediatorsNeoplasmsReceptors, Pattern RecognitionCytokinesInflammation MediatorsReceptors, Pattern RecognitionAutoimmunityCancerDC-related diseasesDendritic cellsResident DCs

Identifiers

PMID26906720
PMCPMC4818737
OpenAlexW2275990891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.