Evidence map›Paper›PMID 26906471›Full record

ReviewNanomedicine (London, England)2016

Nanotechnology in diagnosis and treatment of coronary artery disease.

Mahdi Karimi, Hossein Zare, Amirala Bakhshian Nik, Narges Yazdani, Mohammad Hamrang, Elmira Mohamed, Parham Sahandi Zangabad, Seyed Masoud Moosavi Basri, Leila Bakhtiari, Michael R Hamblin

Open access · greenAbstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Carbon Nanotubes: Smart Drug/Gene Delivery Carriers.International journal of nanomedicine · 2021
    Review
  16. Light: A Magical Tool for Controlled Drug Delivery.Advanced functional materials · 2020
    Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Mahdi KarimiDepartment of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Hossein ZareBiomaterials Group, Materials Science & Engineering Department, Iran University of Science & Technology, P.O. Box 1684613114 Tehran, Iran.
Amirala Bakhshian NikDivision of Biomedical Engineering, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran 1439957131 Tehran, Iran.
Narges YazdaniBiomaterials Group, Materials Science & Engineering Department, Iran University of Science & Technology, P.O. Box 1684613114 Tehran, Iran.
Mohammad HamrangBiomaterials Group, Materials Science & Engineering Department, Iran University of Science & Technology, P.O. Box 1684613114 Tehran, Iran.
Elmira MohamedBiomaterials Group, Materials Science & Engineering Department, Iran University of Science & Technology, P.O. Box 1684613114 Tehran, Iran.
Parham Sahandi ZangabadDepartment of Materials Science & Engineering, Sharif University of Technology, P.O. Box 11365-9466, 14588 Tehran, Iran.
Seyed Masoud Moosavi BasriSchool of Computer Science, Institute for Research in Fundamental Sciences, Tehran, Iran.
Leila BakhtiariBiomaterials Group, Materials Science & Engineering Department, Iran University of Science & Technology, P.O. Box 1684613114 Tehran, Iran.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Iran University of Science and Technology · IRHarvard University · USIran University of Medical Sciences · IRShahid Beheshti University · IRSharif University of Technology · IRUniversity of Tehran · IR

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
NIAID NIH HHS R01 AI050875NIAID NIH HHS R01AI050875
6 · The paper itself

Abstract

Nanotechnology could provide a new complementary approach to treat coronary artery disease (CAD) which is now one of the biggest killers in the Western world. The course of events, which leads to atherosclerosis and CAD, involves many biological factors and cellular disease processes which may be mitigated by therapeutic methods enhanced by nanotechnology. Nanoparticles can provide a variety of delivery systems for cargoes such as drugs and genes that can address many problems within the arteries. In order to improve the performance of current stents, nanotechnology provides different nanomaterial coatings, in addition to controlled-release nanocarriers, to prevent in-stent restenosis. Nanotechnology can increase the efficiency of drugs, improve local and systematic delivery to atherosclerotic plaques and reduce the inflammatory or angiogenic response after intravascular intervention. Nanocarriers have potential for delivery of imaging and diagnostic agents to precisely targeted destinations. This review paper will cover the current applications and future outlook of nanotechnology, as well as the main diagnostic methods, in the treatment of CAD.

Indexed as

Coronary Artery DiseaseDrug CarriersHumansNanoparticlesNanotechnologyPlaque, AtheroscleroticDrug Carriersatherosclerosiscoronary artery diseasenanocarriersnanotechnologyrestenosisstent coatingsvulnerable plaque

Identifiers

PMID26906471
PMCPMC4794112
OpenAlexW2280198161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.