ArticleThe Journal of antibiotics2016
Cladosporinone, a new viriditoxin derivative from the hypersaline lake derived fungus Cladosporium cladosporioides.
Article in The Journal of antibiotics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Draft genome sequence and annotation of fungal pathogen Cladosporium tenuissimum SHK1100 causing postharvest sooty spot of fig fruit.BMC genomic data · 2026Article
- Fungal symbionts of marine organisms: The case ofAIMS microbiology · 2026Review
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism.Cell death & disease · 2022Article
- Total Heterologous Biosynthesis of Fungal Natural Products inJournal of natural products · 2022Review
- Dynamic Fluctuation and Niche Differentiation of Fungal Pathogens Infecting Bell Pepper Plants.Applied and environmental microbiology · 2022Article
- Subcellular localization of fungal specialized metabolites.Fungal biology and biotechnology · 2022Review
- Untapped Potential of Marine-AssociatedMarine drugs · 2021Review
- Phylogenetic and Functional Diversity of Saprolegniales and Fungi Isolated from Temperate Lakes in Northeast Germany.Journal of fungi (Basel, Switzerland) · 2021Article
- The GenusMolecules (Basel, Switzerland) · 2021Review
- Mycopyranone: a 8,8'-binaphthopyranone with potent anti-MRSA activity from the fungusTetrahedron letters · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new cytotoxic viriditoxin derivative, cladosporinone (1), along with the known viriditoxin (2) and two viriditoxin derivatives (3 and 4) were obtained from the fungus Cladosporium cladosporioides isolated from the sediment of a hypersaline lake in Egypt. The structure of the new compound (1) was determined by 1D and 2D NMR measurements as well as by high-resolution ESIMS and electronic circular dichroism spectroscopy. All isolated compounds were studied for their cytotoxicity against the murine lymphoma cell line L5187Y and for their antibiotic activity against several pathogenic bacteria. Viriditoxin (2) was the most active compound in both bioassays. Compound 1 also exhibited strong cytotoxicity against the murine lymphoma cell line L5187Y with an IC50 value of 0.88 μm, whereas its antibiotic activity was weak.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.