Evidence map›Paper›PMID 26905429›Full record

ArticleBMC research notes2016

Sero-prevalence and associated risk factors for hepatitis C virus infection among voluntary counseling testing and anti retroviral treatment clinic attendants in Adwa hospital, northern Ethiopia.

Ataklti Hailu Atsbaha, Tsehaye Asmelash Dejen, Rashmi Belodu, Konjit Getachew, Muthupandian Saravanan, Araya Gebreyesus Wasihun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ataklti Hailu AtsbahaTigray Regional Health and Research Laboratory, P.O.Box: 1807, Mekelle, Ethiopia. ataklti.hailu2012@gmail.com.
Tsehaye Asmelash DejenDepartment of Medical Microbiology and Immunology, Institute of Biomedical Science, College of Health Sciences, Mekelle University, P.O.Box: 1871, Mekelle, Ethiopia. tsehaye93@gmail.com.
Rashmi BeloduDepartment of Medical Microbiology and Immunology, Institute of Biomedical Science, College of Health Sciences, Mekelle University, P.O.Box: 1871, Mekelle, Ethiopia. drbrashmi@gmail.com.
Konjit GetachewDepartment of Medical Microbiology and Immunology, Institute of Biomedical Science, College of Health Sciences, Mekelle University, P.O.Box: 1871, Mekelle, Ethiopia. koyeget@gmail.com.
Muthupandian SaravananDepartment of Medical Microbiology and Immunology, Institute of Biomedical Science, College of Health Sciences, Mekelle University, P.O.Box: 1871, Mekelle, Ethiopia. bioinfosaran@gmail.com.
Araya Gebreyesus WasihunDepartment of Medical Microbiology and Immunology, Institute of Biomedical Science, College of Health Sciences, Mekelle University, P.O.Box: 1871, Mekelle, Ethiopia. araya13e25@gmail.com.
Mekelle University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) is a major health concern where about 3% of the world's population is infected globally. In Ethiopia the prevalence ranges from 0.9 to 1.3% in the general populations. Human immune deficiency virus (HIV) patients due to their weak immune response are heavily affected by the virus. There is no data on magnitude and associated risk factors for HCV infection among voluntary counseling, testing center and anti retroviral treatment clinic Attendants in the study area. Therefore, the aim of this study was to determine the sero-prevalence and associated risk factors for HCV infection among voluntary counseling testing and anti retroviral treatment clinic attendants Adwa general hospital.

methodsCross sectional study was carried out among 302 participants (151 HIV-negative from VCT and 151 HIV-positive from ART follow up) clinics of Adwa hospital from September to December, 2014. About 5 ml of venous blood samples were collected from study participants for anti HCV antibody tests. Univariate analyses were used to identify associated variables with anti HCV positivity. Variables having p < 0.05 were considered as statistically significant association.

resultsOut of the total 302 participants, 52.6% of them were females and 47.4% males. The mean age of the participants was 34.1 year (SD ± 10.5). The overall sero-prevalence of HCV in this study was 4.3%. The prevalence HCV (6.6%) was higher among the ART clinic attendants than the VCT (2%) clinic attendants. History of hospitalization (p = 0.001), tooth extraction (p = 0.018) and blood transfusion (p = 0.041) showed statistically significant association with anti-HCV antibody.

conclusionHCV sero-prevalence in this study was high. The prevalence was three fold higher among HIV positive patients than their counter parts. Thus, screening of HCV should be done among HIV patients for close monitoring and better management in HIV patients.

Indexed as

Antiretroviral Therapy, Highly ActiveAdultCoinfectionCross-Sectional StudiesDirective CounselingEthiopiaFemaleHepacivirusHepatitis CHepatitis C AntibodiesHIVHIV InfectionsHospitals, GeneralHumansMaleMiddle AgedHepatitis C Antibodies

Identifiers

PMID26905429
PMCPMC4765222
OpenAlexW2277998525

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.