Evidence map›Paper›PMID 26905274›Full record

ReviewCurrent oncology reports2016

Advances in the Management of Anal Cancer.

Diana R Julie, Karyn A Goodman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Proton beam radiotherapy for anal and rectal cancers.Journal of gastrointestinal oncology · 2020
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Diana R JulieMemorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA. diana.r.julie@gmail.com.
Karyn A GoodmanDepartment of Radiation Oncology, University of Colorado School of Medicine, 1665 Aurora Court, Suite 1032 MS F706, Aurora, CO, 80045, USA. karyn.goodman@ucdenver.edu.
Memorial Sloan Kettering Cancer Center · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although anal squamous cell carcinoma (ASCC) is an uncommon malignancy, its incidence has been increasing markedly in recent decades due to its association with human papilloma virus (HPV) infection. The well-established standard of care for localized ASCC consists of the combination of 5-fluorouracil (5FU) and mitomycin (MMC) chemotherapy, concurrent with external beam radiation therapy (EBRT). However, newer techniques are being actively pursued, including the use of newer radiation therapy (RT) technologies, such as intensity-modulated radiation therapy (IMRT). The areas of debate and development include the dosing and timing of MMC delivery, the role of cisplatin chemotherapy as an alternative to MMC, the replacement of the standard 96-h infusion of 5FU with oral capecitabine, the use of targeted chemotherapy agents, and the duration and dose of RT.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsAnus NeoplasmsCapecitabineCisplatinFemaleFluorouracilHumansInduction ChemotherapyMass ScreeningMitomycinPapillomavirus InfectionsPapillomavirus VaccinesRadiation DosageRadiotherapy, Intensity-ModulatedCapecitabineCisplatinFluorouracilMitomycinPapillomavirus VaccinesAnal cancerDefinitive chemoradiationHuman papilloma virusIntensity-modulated radiotherapySquamous cell carcinoma

Identifiers

PMID26905274
OpenAlexW2285292834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.