Evidence map›Paper›PMID 26904711›Full record

ArticleData in brief2015

Data detailing the platelet acetyl-lysine proteome.

Joseph E Aslan, Larry L David, Owen J T McCarty

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Joseph E AslanDepartments of Biomedical Engineering, Portland, OR 97239, USA; Cell and Developmental Biology, Portland, OR 97239, USA; Knight Cardiovascular Institute, Portland, OR 97239, USA.
Larry L DavidProteomics Shared Resource, Oregon Health & Science University, Portland, OR 97239, USA.
Owen J T McCartyDepartments of Biomedical Engineering, Portland, OR 97239, USA; Cell and Developmental Biology, Portland, OR 97239, USA; Division of Hematology & Medical Oncology School of Medicine, Portland, OR 97239, USA.
Cardiovascular Institute of the South · USOregon Health & Science University · USUniversity of Portland · US

Funding

Understanding the origins of rapid recurrence of pancreatic cancer after resectionP30CA069533 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Luiz Eduardo Bertassoni · 1997 to 2026
$60.5M
Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
Characterization of Coagulation Factor-platelet Interactions: Role of FXIR01HL101972 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Owen J McCarty · 2010 to 2026
$8.5M
LTQ Orbitrap VelosS10OD012246 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI DAVID, LARRY L · 2012 to 2012
$854k
LINEAR ION TRAP MASS SPECTROMETER: KIDNEYS10RR020863 · NCRR · OREGON HEALTH AND SCIENCE UNIVERSITY · PI DAVID, LARRY L · 2005 to 2005
$305k
NCI NIH HHS P30 CA069533NCRR NIH HHS S10 RR020863NEI NIH HHS P30 EY010572NHLBI NIH HHS R01 HL101972NIH HHS S10 OD012246
6 · The paper itself

Abstract

Here we detail proteomics data that describe the acetyl-lysine proteome of blood platelets (Aslan et al., 2015 [1]). An affinity purification - mass spectrometry (AP-MS) approach was used to identify proteins modified by Nε-lysine acetylation in quiescent, washed human platelets. The data provide insights into potential regulatory mechanisms of platelet function mediated by protein lysine acetylation. Additionally, as platelets are anucleate and lack histone proteins, they offer a unique and valuable system to study the regulation of cytosolic proteins by lysine acetylation. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium (Vizcaino et al., 2014 [2]) via with PRIDE partner repository with the dataset identifier PXD002332.

Indexed as

AcetylationHemostasisPlateletsProteomics

Identifiers

PMID26904711
PMCPMC4726637
OpenAlexW1871281955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.