Evidence map›Paper›PMID 26904607›Full record

ArticleInternational journal of food science2013

Bioactivity of Nonedible Parts of Punica granatum L.: A Potential Source of Functional Ingredients.

Nawraj Rummun, Jhoti Somanah, Srishti Ramsaha, Theeshan Bahorun, Vidushi S Neergheen-Bhujun

Open access · goldAbstract read
In one paragraph

Article in International journal of food science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  8. Novel assay to measure chromosome instability identifiesFrontiers in bioengineering and biotechnology · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Pharmaceuticals (Basel, Switzerland) · 2020
    Article
  13. Article
  14. Article
  15. Apoptotic effects of non-edible parts of Punica granatum on human multiple myeloma cells.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nawraj RummunDepartment of Health Sciences, Faculty of Science, University of Mauritius, Réduit, Mauritius.ORCID 0000-0002-2077-5247
Jhoti SomanahDepartment of Biosciences, and ANDI Centre of Excellence for Biomedical and Biomaterials Research, University of Mauritius, Réduit, Mauritius.
Srishti RamsahaDepartment of Health Sciences, Faculty of Science and ANDI Centre of Excellence for Biomedical and Biomaterials Research, University of Mauritius, Réduit, Mauritius.
Theeshan BahorunANDI Centre of Excellence for Biomedical and Biomaterials Research, University of Mauritius, Réduit, Mauritius.
Vidushi S Neergheen-BhujunDepartment of Health Sciences, Faculty of Science and ANDI Centre of Excellence for Biomedical and Biomaterials Research, University of Mauritius, Réduit, Mauritius.
University of Mauritius · MU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Punica granatum L. has a long standing culinary and medicinal traditional use in Mauritius. This prompted a comparative study to determine the bioefficacy of the flower, peel, leaf, stem, and seed extracts of the Mauritian P. granatum. The flower and peel extracts resulting from organic solvent extraction exhibited strong antioxidant activities which correlated with the high levels of total phenolics, flavonoids, and proanthocyanidins. The peel extract had the most potent scavenging capacity reflected by high Trolox equivalent antioxidant capacity value (5206.01 ± 578.48 μmol/g air dry weight), very low IC50 values for hypochlorous acid (0.004 ± 0.001 mg air dry weight/mL), and hydroxyl radicals scavenging (0.111 ± 0.001 mg air dry weight/mL). Peel extracts also significantly inhibited S. mutans (P < 0.001), S. mitis (P < 0.001), and L. acidophilus (P < 0.05) growth compared to ciprofloxacin. The flower extract exhibited high ferric reducing, nitric oxide scavenging, and iron (II) ions chelation and significantly inhibited microsomal lipid peroxidation. Furthermore, it showed a dose-dependent inhibition of xanthine oxidase with an IC50 value of 0.058 ± 0.011 mg air dry weight/mL. This study showed that nonedible parts of cultivated pomegranates, that are generally discarded, are bioactive in multiassay systems thereby suggesting their potential use as natural prophylactics and in food applications.

Identifiers

PMID26904607
PMCPMC4745514
OpenAlexW2156766338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.