Evidence map›Paper›PMID 26904464›Full record

ReviewIndian journal of endocrinology and metabolism

Diabetes insipidus: The other diabetes.

Sanjay Kalra, Abdul Hamid Zargar, Sunil M Jain, Bipin Sethi, Subhankar Chowdhury, Awadhesh Kumar Singh, Nihal Thomas, A G Unnikrishnan, Piya Ballani Thakkar, Harshad Malve

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Self-Amplifying RNA Approach for Protein Replacement Therapy.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. Approach to the Patient: Management of Pituitary Hormone Replacement Through Transition.The Journal of clinical endocrinology and metabolism · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. A Novel Mutation in theJournal of clinical research in pediatric endocrinology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Sanjay KalraBharti Hospital and BRIDE, Karnal, Haryana, India.
Abdul Hamid ZargarDepartment of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Sunil M JainManaging Director, TOTALL Diabetes Hormone Institute, Indore, Madhya Pradesh, India.
Bipin SethiConsultant Endocrinologist, CARE Hospitals, Hyderabad, Telangana, India.
Subhankar ChowdhuryDepartment of Endocrinology, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.
Awadhesh Kumar SinghGD Diabetes Institute, Kolkata, West Bengal, India; Sun Valley Diabetes and Endocrine Research Centre, Guwahati, Assam, India.
Nihal ThomasDepartment of Endocrinology, Diabetes and Metabolism and Vice-Principal (Research), Christian Medical College, Vellore, Tamil Nadu, India.
A G UnnikrishnanChellaram Diabetes Institute, Pune, Maharashtra, India.
Piya Ballani ThakkarBombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.
Harshad MalveLead Medical, Asia Pacific region, Ferring Pharmaceuticals Pvt. Ltd., Mumbai, Maharashtra, India.
CARE Hospitals · INChristian Medical College, Vellore · INFerring Pharmaceuticals (Switzerland) · CHSher-i-Kashmir Institute of Medical Sciences · INBombay Hospital · INGD Hospital & Diabetes Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes insipidus (DI) is a hereditary or acquired condition which disrupts normal life of persons with the condition; disruption is due to increased thirst and passing of large volumes of urine, even at night. A systematic search of literature for DI was carried out using the PubMed database for the purpose of this review. Central DI due to impaired secretion of arginine vasopressin (AVP) could result from traumatic brain injury, surgery, or tumors whereas nephrogenic DI due to failure of the kidney to respond to AVP is usually inherited. The earliest treatment was posterior pituitary extracts containing vasopressin and oxytocin. The synthetic analog of vasopressin, desmopressin has several benefits over vasopressin. Desmopressin was initially available as intranasal preparation, but now the oral tablet and melt formulations have gained significance, with benefits such as ease of administration and stability at room temperature. Other molecules used for treatment include chlorpropamide, carbamazepine, thiazide diuretics, indapamide, clofibrate, indomethacin, and amiloride. However, desmopressin remains the most widely used drug for the treatment of DI. This review covers the physiology of water balance, causes of DI and various treatment modalities available, with a special focus on desmopressin.

Indexed as

Antidiuretic hormonedesmopressinpolydipsiapolyuriavasopressin

Identifiers

PMID26904464
PMCPMC4743391
OpenAlexW2259140314

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.