Evidence map›Paper›PMID 26904346›Full record

ArticleCase reports in rheumatology2016

Eosinophilic Esophagitis in Two Patients with Systemic Sclerosis.

Tracy M Frech, Kathleen Boynton, Erinn Downs-Kelly, Bryan Jones, John D Kriesel, Kathryn Peterson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tracy M FrechDivision of Rheumatology, Department of Internal Medicine, University of Utah School of Medicine, 4B200 30 N. 1900 E., Salt Lake City, UT 84132, USA.
Kathleen BoyntonDivision of Gastroenterology, Department of Internal Medicine, University of Utah, 50 N Medical Drive, Salt Lake City, UT 84132, USA.
Erinn Downs-KellyDepartment of Anatomic Pathology, University of Utah, 50 N Medical Drive, Salt Lake City, UT 84132, USA.
Bryan JonesDepartment of Ophthalmology, University of Utah, 50 N Medical Drive, Salt Lake City, UT 84132, USA.
John D KrieselDivision of Infectious Diseases, Department of Internal Medicine, University of Utah, 50 N Medical Drive, Salt Lake City, UT 84132, USA.
Kathryn PetersonDivision of Gastroenterology, Department of Internal Medicine, University of Utah, 50 N Medical Drive, Salt Lake City, UT 84132, USA.
University of Utah · US

Funding

University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
University of Utah Center for clinical and Translational ScienceKL2TR001065 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$1.1M
NCATS NIH HHS KL2 TR001065NCATS NIH HHS UL1 TR001067
6 · The paper itself

Abstract

The gastrointestinal tract (GIT) is the most common extracutaneous organ system damaged in systemic sclerosis (SSc) and is the presenting feature in 10% of patients. The esophagus as the portion of the GIT is the most commonly affected and there is an association of gastroesophageal reflux (GER) with SSc interstitial lung disease (ILD). Thus, an aggressive treatment for GER is recommended in all SSc patients with ILD; however, it is recognized that a long-term benefit to this treatment is needed to understand its impact. In this case report we discuss the presence of eosinophilic esophagitis (EoE) in two SSc patients and discuss the role for early EGD in SSc patients with moderate-severe GER symptoms for tissue study. Assessment of esophageal biopsy specimens for the presence of eosinophils and possibly ANA can help elucidate disease pathogenesis and direct therapy, as the presence of EoE in SSc has important management considerations, particularly with regards to dietary modification strategies.

Identifiers

PMID26904346
PMCPMC4745613
OpenAlexW2294485144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.