ReviewJournal of thoracic disease2016
Chronic obstructive pulmonary disease and obstructive sleep apnoea-the overlap syndrome.
Review in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 58 citations in OpenAlex.
- Auto-trilevel versus bilevel positive airway pressure ventilation for hypercapnic overlap syndrome patients.Sleep & breathing = Schlaf & Atmung · 2018Trial
- Association of obstructive airway disease with COMISA: findings from the Turkish sleep apnea database (TURKAPNE) cohort.Sleep & breathing = Schlaf & Atmung · 2026Observational
- Metabolic Syndrome Is Associated with Greater Symptom Burden and Comorbidity in Chronic Obstructive Pulmonary Disease: A Secondary Analysis of the Serbian COPD Registry.Medical sciences (Basel, Switzerland) · 2026Article
- Sleep phenotypes and clinical outcomes in individuals with chronic obstructive pulmonary disease: A cohort study.Sleep & breathing = Schlaf & Atmung · 2026Article
- COPD-OSA overlap syndrome: inflammatory and oxidative stress mechanisms, biomarkers, and clinical implications.Frontiers in medicine · 2026Review
- Sleep, health conditions and quality of life among professors at higher education institutions in Brazil: baseline data from the RESPIRA cohort.BMC public health · 2025Article
- Overlapping obstructive sleep apnea and chronic obstructive pulmonary disease in patients undergoing percutaneous coronary intervention.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Insights into the Overlap of Chronic Obstructive Pulmonary Disease and Sleep Apnea: Experience from the Clinic of Pneumology, Târgu Mureș.Clinics and practice · 2024Article
- Inclusion of blood pressure parameter increases predictive capability of severe obstructive sleep apnea: A decision tree approach.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Correlation of objective and subjective sleep parameters with fatigue and depression in kidney transplant recipients.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- The Overlap Syndrome: A Combination of Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea.Cureus · 2024Review
- Sleep and cardiometabolic comorbidities in the obstructive sleep apnoea-COPD overlap syndrome: data from the European Sleep Apnoea Database.ERJ open research · 2023Article
- Main Pathogenic Mechanisms and Recent Advances in COPD Peripheral Skeletal Muscle Wasting.International journal of molecular sciences · 2023Review
- Sensorimotor Cortical Activity during Respiratory Arousals in Obstructive Sleep Apnea.International journal of molecular sciences · 2022Article
- Review of the prevalence, pathogenesis and management of OSA-COPD overlap.Sleep & breathing = Schlaf & Atmung · 2022Review
- Comparison of invasive intubation and noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease and obstructive sleep apnoea syndrome.The Journal of international medical research · 2021Article
- Burden of Comorbidities in Patients with OSAS and COPD-OSAS Overlap Syndrome.Medicina (Kaunas, Lithuania) · 2021Article
- Prospective Study of Nocturnal Desaturation in Patients Receiving Home Oxygen Therapy.Internal medicine (Tokyo, Japan) · 2021Article
- Metabolic Syndrome and Abnormal Peri-Organ or Intra-Organ Fat (APIFat) Deposition in Chronic Obstructive Pulmonary Disease: An Overview.Metabolites · 2020Review
- Prevalence of self-reported sleep problems amongst adults with obstructive airway disease in the NHANES cohort in the United States.Sleep & breathing = Schlaf & Atmung · 2020Observational
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are highly prevalent disorders and the co-existence of both disorders, termed the overlap syndrome, affects at least 1% of the adult population. Patients with the overlap syndrome typically experience more pronounced nocturnal oxygen desaturation and there is a high prevalence of pulmonary hypertension in such patients. Recent evidence suggests that the prevalence of each disorder together is higher than might be predicted by simple prevalence statistics, although the evidence is not clear-cut in this regard. Sleep itself can have several negative effects in patients with COPD. Sleep quality is diminished with reduced amounts of slow wave and rapid-eye-movement (REM) sleep, which may contribute to daytime symptoms such as fatigue and lethargy. Furthermore, normal physiological adaptations during sleep that result in mild hypoventilation in normal subjects are more pronounced in COPD, which can result in clinically important nocturnal oxygen desaturation. Management of sleep disorders in patients with COPD should address both sleep quality and disordered gas exchange. Non-invasive pressure support is beneficial in selected cases, particularly during acute exacerbations associated with respiratory failure, and is particularly helpful in patients with the overlap syndrome. There is limited evidence of benefit from pressure support in the chronic setting in COPD patients without OSA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.