ArticleFrontiers in plant science2016
A Two-Component Regulatory System in Transcriptional Control of Photosystem Stoichiometry: Redox-Dependent and Sodium Ion-Dependent Phosphoryl Transfer from Cyanobacterial Histidine Kinase Hik2 to Response Regulators Rre1 and RppA.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- A functionally selectedApplied and environmental microbiology · 2026Article
- From photosynthetic electron flow to gene regulation: redox signal transduction in cyanobacteria.FEMS microbiology reviews · 2026Review
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- A functionally selectedbioRxiv : the preprint server for biology · 2025Article
- In Vitro Antimicrobial Efficacy Assessment of Ethanolic, Aqueous, and Dual Solvent Extracts of MushroomAntibiotics (Basel, Switzerland) · 2024Article
- Lipids productivity of cyanobacterium Anabaena vaginicola in an internally illuminated photobioreactor using LED bar lights.Scientific reports · 2024Article
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- Plastoquinone pool redox state and control of state transitions in Chlamydomonas reinhardtii in darkness and under illumination.Photosynthesis research · 2023Article
- Exploring the Impacts of Full-Scale Distribution System Orthophosphate Corrosion Control Implementation on the Microbial Ecology of Hydrologically Connected Urban Streams.Microbiology spectrum · 2022Article
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- Novel prokaryotic system employing previously unknown nucleic acids-based receptors.Microbial cell factories · 2022Article
- Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress.BMC molecular and cell biology · 2022Article
- Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators.FEBS letters · 2022Article
- Pangenome Analytics Reveal Two-Component Systems as Conserved Targets in ESKAPEE Pathogens.mSystems · 2021Article
- Regulatory Diversity and Functional Analysis of Two-Component Systems in CyanobacteriumFrontiers in microbiology · 2020Article
- Oligomeric states in sodium ion-dependent regulation of cyanobacterial histidine kinase-2.Protoplasma · 2018Article
- Probing the nucleotide-binding activity of a redox sensor: two-component regulatory control in chloroplasts.Photosynthesis research · 2016Article
- A Proposal for Formation of Archaean Stromatolites before the Advent of Oxygenic Photosynthesis.Frontiers in microbiology · 2016Article
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3 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Two-component systems (TCSs) are ubiquitous signaling units found in prokaryotes. A TCS consists of a sensor histidine kinase and a response regulator protein as signal transducers. These regulatory systems mediate acclimation to various environmental changes by coupling environmental cues to gene expression. Hik2 is a sensor histidine kinase and its gene is found in all cyanobacteria. Hik2 is the homolog of Chloroplast Sensor Kinase (CSK), a protein involved in redox regulation of chloroplast gene expression during changes in light quality in plants and algae. Here we describe biochemical characterization of the signaling mechanism of Hik2 and its phosphotransferase activity. Results presented here indicate that Hik2 undergoes autophosphorylation on a conserved histidine residue, and becomes rapidly dephosphorylated by the action of response regulators Rre1 and RppA. We also show that the autophosphorylation of Hik2 is specifically inhibited by sodium ions.
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