ReviewFrontiers in plant science2015
Heavy Metal Tolerance in Plants: Role of Transcriptomics, Proteomics, Metabolomics, and Ionomics.
Review in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 309 papers.
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Who cites it
309 citing papers in PubMed.
- γ-Aminobutyric Acid Alleviates Cadmium Toxicity and Is Associated with Increased Ascorbate and Glutathione Levels inInternational journal of molecular sciences · 2026Article
- Article
- Plant Responses to Radionuclides and Heavy Metals in Uranium Mining Sites: Mechanisms and Phytoremediation.Biology · 2026Review
- Physiological Adaptation Strategy of the Pseudo-MetallophyteAntioxidants (Basel, Switzerland) · 2026Article
- Integrated transcriptomic and hormonomic insights into cadmium tolerance of aMicrobiology (Reading, England) · 2026Article
- Glutathione and Jasmonic Acid Biosynthesis Coordinate Antioxidant and Hormonal Responses to Alleviate Lead Toxicity inPlants (Basel, Switzerland) · 2026Article
- CRISPR-enabled functional genomics for bolstering plant tolerance to abiotic and biotic stress; a comprehensive review.Functional & integrative genomics · 2026Review
- Harnessing biostimulants to alleviate potentially toxic element stress in vegetable crops.Planta · 2026Review
- PFAS Uptake by Plants in Soils Amended with Biosolids Derived from Wastewater with Industrial Input.ACS environmental Au · 2026Article
- Integrated physiological, biochemical, and transcriptomic analyses reveal lead-induces stress responses and tolerance of bread wheat (Triticum aestivum L.).BMC plant biology · 2026Article
- Mitigation of lead stress in Zea mays L. plants: the role of Trichoderma harzianum Zag-1 in enhancing antioxidant defense and physiological stability.BMC plant biology · 2026Article
- Transporter promiscuity and redox-driven metal partitioning in plant responses to chemically analogous metals.Plant cell reports · 2026Review
- Green synthesized selenium nanoparticles-based amelioration of Cd toxicity in radish using seed priming.Scientific reports · 2026Article
- Health risk assessment and ionomic profiling under cadmium, lead, zinc, and manganese stress in Amaranthus cruentus.BMC plant biology · 2026Article
- Applications of Gene-Editing Technologies in Enhancing Crop Stress Resistance with Emphasis on Rice.Plants (Basel, Switzerland) · 2026Review
- Calcium Signaling as an Emerging Integrator of Manganese Homeostasis inPlants (Basel, Switzerland) · 2026Review
- ZnO and rGO-Based nanoparticles regulate morphophysiological, biochemical, and molecular responses of Phaseolus vulgaris L. under drought and arsenic stress.BMC plant biology · 2026Article
- Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Burkholderia sp. ZF6-mediated mitigation of Cd and Zn stress in contaminated soil: effects on Chinese cabbage growth and rhizosphere microbial communities.Environmental science and pollution research international · 2026Article
- Chloroplast: structural and functional alteration under nickel stress and tolerance mechanism via the omics approach.Plant cell reports · 2026Review
249 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heavy metal contamination of soil and water causing toxicity/stress has become one important constraint to crop productivity and quality. This situation has further worsened by the increasing population growth and inherent food demand. It has been reported in several studies that counterbalancing toxicity due to heavy metal requires complex mechanisms at molecular, biochemical, physiological, cellular, tissue, and whole plant level, which might manifest in terms of improved crop productivity. Recent advances in various disciplines of biological sciences such as metabolomics, transcriptomics, proteomics, etc., have assisted in the characterization of metabolites, transcription factors, and stress-inducible proteins involved in heavy metal tolerance, which in turn can be utilized for generating heavy metal-tolerant crops. This review summarizes various tolerance strategies of plants under heavy metal toxicity covering the role of metabolites (metabolomics), trace elements (ionomics), transcription factors (transcriptomics), various stress-inducible proteins (proteomics) as well as the role of plant hormones. We also provide a glance of some strategies adopted by metal-accumulating plants, also known as "metallophytes."
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