ArticleFrontiers in microbiology2016
Ketide Synthase (KS) Domain Prediction and Analysis of Iterative Type II PKS Gene in Marine Sponge-Associated Actinobacteria Producing Biosurfactants and Antimicrobial Agents.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Marine microbiomes and their expanding role in biotechnological potential: a systematic review.Archives of microbiology · 2026Pooled it
- Sustainable Biocatalytic Cascades: A Versatile Tool in the Synthesis of Natural Products With Therapeutic Potential.Chembiochem : a European journal of chemical biology · 2026Review
- Exploration of bioflocculant production of endophytic bacterium: assessment of characteristics and efficiency of its bioflocculant in wastewater treatment.Environmental science and pollution research international · 2026Article
- Presence of polyketide synthases and nonribosomal peptide synthetase in culturable bacteria associated with Aplysina fulva and Aplysina caissara (Porifera).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Molecular Identification and Characterization of ProbioticMicroorganisms · 2021Article
- A Metataxonomic Approach Reveals Diversified Bacterial Communities in Antarctic Sponges.Marine drugs · 2021Article
- Recent Trends on Biosurfactants With Antimicrobial Activity Produced by Bacteria Associated With Human Health: Different Perspectives on Their Properties, Challenges, and Potential Applications.Frontiers in microbiology · 2021Review
- Exploring Antifouling Activity of Biosurfactants Producing Marine Bacteria Isolated from Gulf of California.International journal of molecular sciences · 2020Article
- Evaluation of Antagonistic and Plant Growth Promoting Potential of Streptomyces sp. TT3 Isolated from Tea (Camellia sinensis) Rhizosphere Soil.Current microbiology · 2020Article
- Marine-Derived Surface Active Agents: Health-Promoting Properties and Blue Biotechnology-Based Applications.Biomolecules · 2020Review
- Marine Biosurfactants: Biosynthesis, Structural Diversity and Biotechnological Applications.Marine drugs · 2019Review
- Diversity, Ecology, and Prevalence of Antimicrobials in Nature.Frontiers in microbiology · 2019Review
- An antibiotic agent pyrrolo[1,2-RSC advances · 2018Article
- Recovering Genomics Clusters of Secondary Metabolites from Lakes Using Genome-Resolved Metagenomics.Frontiers in microbiology · 2018Article
- Synthesis of Nm-PHB (nanomelanin-polyhydroxy butyrate) nanocomposite film and its protective effect against biofilm-forming multi drug resistant Staphylococcus aureus.Scientific reports · 2017Article
- Production of Lipopeptide Biosurfactant by a MarineFrontiers in microbiology · 2017Article
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6 authors.
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Abstract
The important biological macromolecules, such as lipopeptide and glycolipid biosurfactant producing marine actinobacteria were analyzed and their potential linkage between type II polyketide synthase (PKS) genes was explored. A unique feature of type II PKS genes is their high amino acid (AA) sequence homology and conserved gene organization. These enzymes mediate the biosynthesis of polyketide natural products with enormous structural complexity and chemical nature by combinatorial use of various domains. Therefore, deciphering the order of AA sequence encoded by PKS domains tailored the chemical structure of polyketide analogs still remains a great challenge. The present work deals with an in vitro and in silico analysis of PKS type II genes from five actinobacterial species to correlate KS domain architecture and structural features. Our present analysis reveals the unique protein domain organization of iterative type II PKS and KS domain of marine actinobacteria. The findings of this study would have implications in metabolic pathway reconstruction and design of semi-synthetic genomes to achieve rational design of novel natural products.
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