Evidence map›Paper›PMID 26903722›Full record

ArticleOman journal of ophthalmology

Experience of intravitreal injections in a tertiary Hospital in Oman.

Ahmed S Al-Hinai

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Oman journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04588948 (A Pharmacokinetic Study of Intravitreal Aflibercept Injection in Vitrectomized and Non-vitrectomized Eyes With Diabetic Macular Edema), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04588948 phase2withdrawnnot on this map

A Pharmacokinetic Study of Intravitreal Aflibercept Injection in Vitrectomized and Non-vitrectomized Eyes With Diabetic Macular Edema

TypeinterventionalSponsorStanford UniversityRan2020 to 2021Enrolled0ConditionsDiabetic Macular EdemaArmsIntravitreal Aflibercept
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ahmed S Al-HinaiDepartment of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.
Sultan Qaboos University Hospital · OM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo find out statistical data regarding intravitreal injections in an outpatient department setup at a tertiary center in Oman.

designRetrospective chart review.

methodsData collection of patients who underwent intravitreal injections from November 2009 to May 2013 at Sultan Qaboos University Hospital.

resultsThroughout a period of 42 months, a total of 711 intravitreal injections were performed. That included 214 patients (275 eyes). Around one-third of the eyes received two injections or more. The injected agents were bevacizumab (59.8%), ranibizumab (32.3%), triamcinolone (7.5%), and very few patients with endophthalmitis received intravitreal antibiotics and antifungal agents. The three most common indications for the injection therapy were diabetic macular edema (50.9%), choroidal neovascularization (24.3%), and retinal vein occlusive diseases (11.5%). Serious adverse events were rare, and they occurred as ocular (0.9% per patient) and systemic (3.3% per patient). There were 42 eyes received intravitreal triamcinolone, and 24% of them developed intraocular hypertension that required only medical treatment.

conclusionDifferent intravitreal agents are currently used to treat many ocular diseases. Currently, therapy with intravitreal agents is very popular, and it carries a promising outcome with more efficiency and safety.

Indexed as

Antivascular endothelial growth factorschoroidal neovascularizationdiabetic macular edemaintravitrealOmanretinaretinal vascular occlusion

Identifiers

PMID26903722
PMCPMC4738661
OpenAlexW2247699805

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.