ArticleZhongguo fei ai za zhi = Chinese journal of lung cancer2016
[Expression and Clinical Significance of MAGE-C2 in Lung Adenocarcinoma].
Article in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Differential gene expression and network analysis in head and neck squamous cell carcinoma.Molecular and cellular biochemistry · 2022Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study is to detect the expression of melanoma antigen-C2 (MAGE-C2) in lung adenocarcinoma tissues and adjacent non-cancerousous tissues and analyze its clinical significance.
methodsThe expression level of MAGE-C2 mRNA and MAGE-C2 protein were measured in 87 cases of lung adenocarcinoma tissues and adjacent non-cancerous tissues were detected by Real-time fluorescence quantitative PCR and Western blot.
resultsOver-expression of the MAGE-C2 mRNA and MAGE-C2 protein were observed in lung adenocarcinoma tissues (53/87, 60.9%), but nor in adjacent non-cancerous tissues. The expressions of MAGE-C2 mRNA and MAGE-C2 protein were closely associated with clinical stage, metastasis and differentiation (P<0.05). The expression rate of MAGE-C2 mRNA had no relationship with gender, age, smoking (P>0.05). The expression of MAGE-C2 had an adverse effect on overall survival rate (P<0.05).
conclusionsOver-expression of the MAGE-C2 mRNA and protein is existed in lung adenocarcinoma. The high expression of MAGE-C2 may be closely related to the occurrence and development in lung adenocarcinoma. MAGE-C2 may predict a poor prognosis and could be as a novel lung adenocarcinoma molecule marker. .
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