Evidence map›Paper›PMID 26902299›Full record

Observational studyPediatric radiology2016

The classic metaphyseal lesion and traumatic injury.

Jonathan D Thackeray, Jacob Wannemacher, Brent H Adler, Daniel M Lindberg

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Pediatric radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Sentinel injuries in child abuse: a multidisciplinary approach.International journal of legal medicine · 2026
    Article
  3. Article
  4. Article
  5. Osteogenesis Imperfecta or Non-accidental Trauma? The Diagnostic Dilemma in Pediatric Fractures.Journal of the Pediatric Orthopaedic Society of North America · 2025
    Article
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  7. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jonathan D ThackerayDivision of Child and Family Advocacy, Nationwide Children's Hospital, 655 E. Livingston Ave., Columbus, OH, 43205, USA. jonathan.thackeray@nationwidechildrens.org.
Jacob WannemacherThe Ohio State University College of Medicine, Columbus, OH, USA.
Brent H AdlerDepartment of Radiology, Nationwide Children's Hospital, Columbus, OH, USA.
Daniel M LindbergDepartment of Emergency Medicine and The Kempe Center for the Prevention and Treatment of Child Abuse and Neglect, University of Colorado School of Medicine, Denver, CO, USA.
Nationwide Children's Hospital · USThe Ohio State University · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is widely accepted that the classic metaphyseal lesion (CML) is a traumatic lesion, strongly associated with abuse in infants. Nevertheless, various non-traumatic origins for CMLs continue to be suggested in medical and legal settings. No studies to date systematically describe the association of CMLs with other traumatic injuries.

objectiveThe primary objective of this study is to examine the association of CMLs with other traumatic injuries in a large data set of children evaluated for physical abuse. MATERIALS AND

methodsThis was a retrospectively planned secondary analysis of data from a prospective, observational study of children <120 months of age who underwent evaluation by a child abuse physician. For this secondary analysis, we identified all children ≤12 months of age with an identified CML and determined the number and type of additional injuries identified. Descriptive analysis was used to report frequency of additional traumatic injuries.

resultsAmong 2,890 subjects, 119 (4.1%) were identified as having a CML. Of these, 100 (84.0%) had at least one additional (non-CML) fracture. Thirty-three (27.7%) had traumatic brain injury. Nearly half (43.7%) of children had cutaneous injuries. Oropharyngeal injuries were found in 12 (10.1%) children. Abdominal/thoracic injuries were also found in 12 (10.1%) children. In all, 95.8% of children with a CML had at least one additional injury; one in four children had three or more categories of injury.

conclusionCMLs identified in young children are strongly associated with traumatic injuries. Identification of a CML in a young child should prompt a thorough evaluation for physical abuse.

Indexed as

Bone and BonesChild AbuseDatabases, FactualFemaleFractures, BoneHumansInfantInfant, NewbornMaleProspective StudiesRadiographyRetrospective StudiesSoft Tissue InjuriesChild abuseChildrenClassic metaphyseal lesionFracturesRadiography

Identifiers

PMID26902299
OpenAlexW2281780421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.