Evidence map›Paper›PMID 26901709›Full record

ArticleBone marrow transplantation2016

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually.

J R Passweg, H Baldomero, P Bader, C Bonini, S Cesaro, P Dreger, R F Duarte, C Dufour, J Kuball, D Farge-Bancel and 6 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Bone marrow transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
170citing papers in PubMed, 6 pooled it
50.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

170 citing papers in PubMed, 6 syntheses or guidelines pooled it, 393 citations in OpenAlex.

  1. Pooled it
  2. Prognostic value of sarcopenia in survivors of hematological malignances undergoing a hematopoietic stem cell transplantation: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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  6. National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Research Methodology and Study Design Working Group Report.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2017
    Guideline
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110 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 9 countries.

J R PasswegEBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital Basel, Basel, Switzerland.
H BaldomeroEBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital Basel, Basel, Switzerland.
P BaderKlinik für Kinder- und Jugendmedizin, Universitätsklinikum Frankfurt, Goethe-Universität, Frankfurt am Main, Germany.
C BoniniUniversità Vita-Salute San Raffaele, Milan, Italy.
S CesaroPaediatric Haematology Oncology, Policlinico G.B. Rossi, Verona, Italy.
P DregerMedizinische Klinik V, University of Heidelberg, Heidelberg, Germany.
R F DuarteHematology Department, Institut Català d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
C DufourHematology Unit, G.Gaslini Children's Institute, Genova, Italy.
J KuballDepartment of Haematology, University Medical Centre, Utrecht, The Netherlands.
D Farge-BancelService de Médecine Interne, Maladies Autoimmunes et Pathologie Vasculaire, Hôpital St Louis, Paris, France.
A GenneryPaediatric Team Children's BMT Unit, Great North Children's Hospital, Royal Victoria Infirmary, Newcastle University, Newcastle-Upon-Tyne, UK.
N KrögerDepartment of Stem cell Transplantation, University Hospital Eppendorf, Hamburg, Germany.
F LanzaHematology and BMT Unit, Cremona, Italy.
A NaglerChaim Sheba Medical Center, Tel-Hashomer, Israel.
A SuredaHematology Department, Institut Català d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
M MohtyDepartment of Hematology, Hôpital Saint Antoine, Paris, France.
Goethe University Frankfurt · DEHeidelberg University · DEIstituto Giannina Gaslini · ITSheba Medical Center · ILSorbonne Université · FRUniversität Hamburg · DEUniversity Hospital of Basel · CHRoyal Victoria Infirmary · GBUniversity Medical Center Utrecht · NLVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented.

Indexed as

Surveys and QuestionnairesAmyloidosisAnemia, AplasticCord Blood Stem Cell TransplantationEuropeHematopoietic Stem Cell TransplantationHumansNeoplasmsPatient Care TeamTissue DonorsTransplantation, AutologousTransplantation, HaploidenticalTransplantation, Homologous

Identifiers

PMID26901709
PMCPMC4895175
OpenAlexW2284574660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.