Evidence map›Paper›PMID 26901454›Full record

ArticleWomen's health (London, England)2016

Is anti-Müllerian hormone associated with IVF outcomes in young patients with diminished ovarian reserve?

Nigel Pereira, Robert Setton, Allison C Petrini, Jovana P Lekovich, Rony T Elias, Steven D Spandorfer

Open access · goldAbstract read
In one paragraph

Article in Women's health (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Preimplantation Genetic Testing for Breast Cancer.Nigerian medical journal : journal of the Nigeria Medical Association
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nigel PereiraThe Ronald O Perelman & Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA.
Robert SettonDepartment of Obstetrics & Gynecology, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA.
Allison C PetriniDepartment of Obstetrics & Gynecology, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA.
Jovana P LekovichThe Ronald O Perelman & Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA.
Rony T EliasThe Ronald O Perelman & Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA.
Steven D SpandorferThe Ronald O Perelman & Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, 1300 York Ave., New York, NY 10065, USA.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate whether anti-Müllerian hormone (AMH) is associated with IVF cycle outcomes in young patients with diminished ovarian reserve. MATERIALS &

methodsRetrospective study of patients <35 years of age undergoing fresh IVF who had at least two 8-cell, day-3 embryos transferred with grades 1, 1.5 or 2. Patients were subgrouped, a priori, based on serum AMH levels: <1 or >1 ng/ml and <0.5 or >0.5 ng/ml.

resultsIn total, 1005 patients were included. Patients in the >1 ng/ml group required lesser gonadotropins compared with the <1 ng/ml and the <0.5 ng/ml group. More oocytes were retrieved from the same group compared with the latter two (p < 0.001). Despite these differences, the overall rates of clinical pregnancy, spontaneous abortion and live birth were comparable between the two groups.

conclusionIn patients with diminished ovarian reserve who have good quality embryos, AMH is not associated with clinical pregnancy, spontaneous miscarriage or live birth rates.

Indexed as

Pregnancy RateAdultAnti-Mullerian HormoneFemaleFertilization in VitroFollicle Stimulating HormoneHumansMaleOvulation InductionPregnancyRetrospective StudiesYoung AdultAnti-Mullerian HormoneFollicle Stimulating Hormoneanti-Müllerian hormonediminished ovarian reserveIVFoutcomesprediction

Identifiers

PMID26901454
PMCPMC5375045
OpenAlexW2273649011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.