Evidence map›Paper›PMID 26901417›Full record

Trial reportPloS one2016

Long Term Outcomes of a Geriatric Liaison Intervention in Frail Elderly Cancer Patients.

Liesbeth Hempenius, Joris P J Slaets, Dieneke van Asselt, Truuske H de Bock, Theo Wiggers, Barbara L van Leeuwen

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 9 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 9 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Informational support for depression and quality of life improvements in older patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Liesbeth HempeniusUniversity Center for Geriatric Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Joris P J SlaetsUniversity Center for Geriatric Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Dieneke van AsseltDepartment of Geriatrics, Radboud University Medical Center, Nijmegen, the Netherlands.
Truuske H de BockDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Theo WiggersDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Barbara L van LeeuwenDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
University Medical Center Groningen · NLUniversity of Groningen · NLMedisch Centrum Leeuwarden · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the long term effects after discharge of a hospital-based geriatric liaison intervention to prevent postoperative delirium in frail elderly cancer patients treated with an elective surgical procedure for a solid tumour. In addition, the effect of a postoperative delirium on long term outcomes was examined.

methodsA three month follow-up was performed in participants of the Liaison Intervention in Frail Elderly study, a multicentre, prospective, randomized, controlled trial. Patients were randomized to standard treatment or a geriatric liaison intervention. The intervention consisted of a preoperative geriatric consultation, an individual treatment plan targeted at risk factors for delirium and daily visits by a geriatric nurse during the hospital stay. The long term outcomes included: mortality, rehospitalisation, Activities of Daily Living (ADL) functioning, return to the independent pre-operative living situation, use of supportive care, cognitive functioning and health related quality of life.

resultsData of 260 patients (intervention n = 127, Control n = 133) were analysed. There were no differences between the intervention group and usual-care group for any of the outcomes three months after discharge. The presence of postoperative delirium was associated with: an increased risk of decline in ADL functioning (OR: 2.65, 95% CI: 1.02-6.88), an increased use of supportive assistance (OR: 2.45, 95% CI: 1.02-5.87) and a decreased chance to return to the independent preoperative living situation (OR: 0.18, 95% CI: 0.07-0.49).

conclusionsA hospital-based geriatric liaison intervention for the prevention of postoperative delirium in frail elderly cancer patients undergoing elective surgery for a solid tumour did not improve outcomes 3 months after discharge from hospital. The negative effect of a postoperative delirium on late outcome was confirmed.

trial registrationNederlands Trial Register, Trial ID NTR 823.

Indexed as

NeoplasmsAgedAged, 80 and overDeliriumElective Surgical ProceduresFemaleFrail ElderlyGeriatric AssessmentHumansLength of StayMalePostoperative ComplicationsProspective StudiesQuality of LifeRisk Factors

Identifiers

PMID26901417
PMCPMC4762573
OpenAlexW2278254757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.