Evidence map›Paper›PMID 26901345›Full record

ArticleObesity facts2016

Hyperinsulinemic Hypoglycemia after Bariatric Surgery: Diagnosis and Management Experience from a Spanish Multicenter Registry.

Nuria Vilarrasa, Albert Goday, Miguel Angel Rubio, Assumpta Caixàs, Silvia Pellitero, Andrea Ciudin, Alfonso Calañas, José Ignacio Botella, Irene Bretón, María José Morales and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Obesity facts, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 172 citations in OpenAlex.

  1. Trial
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  6. Review
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  9. Review
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  11. Pramlintide for post-bariatric hypoglycaemia.Diabetes, obesity & metabolism · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Somatostatin analogues for the treatment of hyperinsulinaemic hypoglycaemia.Therapeutic advances in endocrinology and metabolism · 2020
    Review
  17. Review
  18. Medical nutrition therapy for post-bariatric hypoglycemia: practical insights.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Nuria VilarrasaDepartment of Endocrinology and Nutrition, Hospital Universitario de Bellvitge-IDIBELL, Lx00B4;Hospitalet de Llobregat, Barcelona, Spain.
Albert Goday
Miguel Angel Rubio
Assumpta Caixàs
Silvia Pellitero
Andrea Ciudin
Alfonso Calañas
José Ignacio Botella
Irene Bretón
María José Morales
María Jesús Díaz-Fernández
Pedro Pablo García-Luna
Albert Lecube
Ajuntament de L’Hospitalet · ESBellvitge University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere postprandial hypoglycemia after bariatric surgery is a rare but invalidating complication. Our aim was to describe the different tests performed for its diagnosis and their outcomes as well as the response to the prescribed pharmacological and surgical treatments.

methodsMulticenter, retrospective systematic review of cases with recurrent severe postprandial hypoglycemia.

resultsOver 11 years of follow-up, 22 patients were identified. The test most used to provoke hypoglycemia was the oral glucose load test followed by the mixed meal test which was the least standardized test. With pharmacological treatment, 3 patients were symptom-free (with octreotide) and in 12 patients hypoglycemic episodes were attenuated. Seven patients had persistent hypoglycemic episodes and underwent surgery. Partial pancreatectomy was performed in 3 patients who had positive selective arterial calcium stimulation, and nesidioblastosis was confirmed in 2 patients. Reconversion to normal anatomy was performed in 3 patients, and 1 patient underwent a resection of the 'candy cane' roux limb, with resolution of hypoglycemia in all cases.

conclusionsThere is high heterogeneity in the evaluation and treatment options for postoperative hypoglycemia. In patients that do not respond to pharmacological treatment, reconstruction of gastrojejunal continuity may be the safest and most successful procedure.

Indexed as

AdultBariatric SurgeryFemaleGlucose Tolerance TestHumansHyperinsulinismHypoglycemiaIncidenceJejunumMaleMiddle AgedNesidioblastosisOctreotidePancreatectomyRegistriesRetrospective StudiesOctreotide

Identifiers

PMID26901345
PMCPMC5644871
OpenAlexW2276159333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.