Evidence map›Paper›PMID 26901290›Full record

ReviewCurrent opinion in cell biology2016

Adder and a coarse-grained approach to cell size homeostasis in bacteria.

John T Sauls, Dongyang Li, Suckjoon Jun

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 140 citations in OpenAlex.

  1. Simulation-based inference captures non-Markovian effects as exemplified in protein production kinetics through cell division.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  2. Clocks and Dominoes: Timing Mechanisms of Embryogenesis.bioRxiv : the preprint server for biology · 2026
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  9. A GeneralizedbioRxiv : the preprint server for biology · 2024
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  12. Balance between asymmetric allocation and repair of somatic damage in unicellular life forms as an ancient form of r/K selection.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John T SaulsUCSD Physics and Molecular Biology, 9500 Gilman Dr., La Jolla, CA 92093, United States.
Dongyang LiUCSD Physics and Molecular Biology, 9500 Gilman Dr., La Jolla, CA 92093, United States.
Suckjoon JunUCSD Physics and Molecular Biology, 9500 Gilman Dr., La Jolla, CA 92093, United States. Electronic address: suckjoon.jun@gmail.com.
University of California, San Diego · US

Funding

GRADUATE TRAINING PROGRAM IN BIONFORMATICST32GM008806 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAFNA, VINEET, REN, BING · 2001 to 2020
$6.2M
R01 Supplement for Undergraduate Summer Research 2020R01GM118565 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JUN, SUCKJOON · 2016 to 2020
$1.7M
NIGMS NIH HHS R01 GM118565NIGMS NIH HHS T32 GM008806
6 · The paper itself

Abstract

Cell size control and homeostasis is a long-standing subject in biology. Recent experimental work provides extensive evidence for a simple, quantitative size homeostasis principle coined adder (as opposed to sizer or timer). The adder principle provides unexpected insights into how bacteria maintain their size without employing a feedback mechanism. We review the genesis of adder and recent cell size homeostasis study on evolutionarily divergent bacterial organisms and beyond. We propose new coarse-grained approaches to understand the underlying mechanisms of cell size control at the whole cell level.

Indexed as

HomeostasisBacteriaBiological Evolution

Identifiers

PMID26901290
PMCPMC5660915
OpenAlexW2273741954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.