ReviewPathogens (Basel, Switzerland)2016
Perspective: Adhesion Mediated Signal Transduction in Bacterial Pathogens.
Review in Pathogens (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- The role of leptospiral proteins in immune evasion and inflammatory response stimulation in HEK293T cell monolayers.Frontiers in immunology · 2025Article
- Decorating bacteria with self-assembled synthetic receptors.Nature communications · 2020Article
- Arginine within a specific motif near the N-terminal of FimY is critical for the maximal production of type 1 fimbriae in Salmonella enterica serovar Typhimurium.MicrobiologyOpen · 2019Article
- The Effect of Recombinant Human Erythropoietin on Bacterial Growth: A Dual-Edged Sword.Kidney diseases (Basel, Switzerland) · 2019Review
- Determination of the expression of three fimbrial subunit proteins in cultured Trueperella pyogenes.Acta veterinaria Scandinavica · 2018Article
- Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria.PLoS biology · 2018Article
- Prediction of Broad-Spectrum Pathogen Attachment to Coating Materials for Biomedical Devices.ACS applied materials & interfaces · 2018Article
- Against the tide: the role of bacterial adhesion in host colonization.Biochemical Society transactions · 2016Review
- Analysis of the contribution of MTP and the predicted Flp pilus genes to Mycobacterium tuberculosis pathogenesis.Microbiology (Reading, England) · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the infection process, pathogenic bacteria undergo large-scale transcriptional changes to promote virulence and increase intrahost survival. While much of this reprogramming occurs in response to changes in chemical environment, such as nutrient availability and pH, there is increasing evidence that adhesion to host-tissue can also trigger signal transduction pathways resulting in differential gene expression. Determining the molecular mechanisms of adhesion-mediated signaling requires disentangling the contributions of chemical and mechanical stimuli. Here we highlight recent work demonstrating that surface attachment drives a transcriptional response in bacterial pathogens, including uropathogenic Escherichia coli (E. coli), and discuss the complexity of experimental design when dissecting the specific role of adhesion-mediated signaling during infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.