ReviewInternational journal of molecular sciences2016
The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
210 citing papers in PubMed, 1 synthesis or guideline pooled it, 657 citations in OpenAlex.
- Evaluating efficacy, safety, and innovation in skin care applications of essential oils: a systematic review.Frontiers in medicine · 2025Pooled it
- Trial
- Green extraction routes for conversion of Nerium oleander L. biomass into bioactive agents: phytochemical insights and antimicrobial promise.BMC complementary medicine and therapies · 2026Article
- Chemical Composition, Biological Activities and Application ofMolecules (Basel, Switzerland) · 2026Review
- GC-Ms, UHPLC-MS/MSChemistry & biodiversity · 2026Article
- Phytochemical Characterisation and Skin-Relevant In Vitro Biological Activity of Leaf Extracts from SelectedMolecules (Basel, Switzerland) · 2026Article
- Botanical Origin-Dependent Phytochemical Profiles and Pharmaceutical Properties of Medical-Grade Honeys: Transdermal Delivery and Antibacterial Efficacy in a Wound Fluid Model.Molecules (Basel, Switzerland) · 2026Article
- The Influence of Water Extraction Methods on the Isolation of Polyphenols and Tannins from Various Ericaceae and Rosaceae Species.Plants (Basel, Switzerland) · 2026Article
- Antioxidant Constituents of Hops (Materials (Basel, Switzerland) · 2026Article
- Medicinal Honeys from Oceania: An Updated Review on Their Bioactive Constituents and Health Applications.Biotech (Basel (Switzerland)) · 2026Review
- Potentiation of the Pharmacological Effects of anPharmaceutics · 2026Article
- Activity ofFrontiers in pharmacology · 2026Article
- Phytoextracts as Natural Anti-Aging Agents: Mechanisms and Strategies for Skin Rejuvenation.Current aging science · 2026Review
- Phenolic and fatty acid profile and antioxidant activity ofOpen medicine (Warsaw, Poland) · 2026Article
- A comprehensive overview of strategies to improve blueberry fruit quality.Frontiers in plant science · 2026Review
- Therapeutic Potential of Chitosan-Based and Related Nanocomposite Systems in Wound Management: A Review.International journal of molecular sciences · 2025Review
- Antibacterial, Photoprotective, Anti-Inflammatory, and Selected Anticancer Properties of Honokiol Extracted from Plants of the GenusInternational journal of molecular sciences · 2025Review
- Evaluation ofMolecules (Basel, Switzerland) · 2025Article
- Sustainable Olive Pomace Extracts for Skin Barrier Support.Pharmaceutics · 2025Article
- In vitro and in silico evaluation of phytocompounds from Leucaena leucocephala and Entada phaseoloides targeting DNA gyrase, topoisomerase II, AKT1.Scientific reports · 2025Article
150 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phenolic compounds constitute a group of secondary metabolites which have important functions in plants. Besides the beneficial effects on the plant host, phenolic metabolites (polyphenols) exhibit a series of biological properties that influence the human in a health-promoting manner. Evidence suggests that people can benefit from plant phenolics obtained either by the diet or through skin application, because they can alleviate symptoms and inhibit the development of various skin disorders. Due to their natural origin and low toxicity, phenolic compounds are a promising tool in eliminating the causes and effects of skin aging, skin diseases, and skin damage, including wounds and burns. Polyphenols also act protectively and help prevent or attenuate the progression of certain skin disorders, both embarrassing minor problems (e.g., wrinkles, acne) or serious, potentially life-threatening diseases such as cancer. This paper reviews the latest reports on the potential therapy of skin disorders through treatment with phenolic compounds, considering mostly a single specific compound or a combination of compounds in a plant extract.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.