Evidence map›Paper›PMID 26901172›Full record

ReviewMolecules (Basel, Switzerland)2016

Molecular Mechanisms of Inhibition of Streptococcus Species by Phytochemicals.

Soheila Abachi, Song Lee, H P Vasantha Rupasinghe

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
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  9. Review
  10. Antimicrobial Properties ofPharmaceutics · 2021
    Article
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  20. Oxidative medicine and cellular longevity · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Soheila AbachiFaculty of Agriculture, Dalhousie University, Truro, NS PO Box 550, Canada. sh764873@dal.ca.
Song LeeFaculty of Dentistry, Dalhousie University, Halifax, NS PO Box 15000, Canada. Song.Lee@dal.ca.
H P Vasantha RupasingheFaculty of Agriculture, Dalhousie University, Truro, NS PO Box 550, Canada. vrupasinghe@dal.ca.
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review paper summarizes the antibacterial effects of phytochemicals of various medicinal plants against pathogenic and cariogenic streptococcal species. The information suggests that these phytochemicals have potential as alternatives to the classical antibiotics currently used for the treatment of streptococcal infections. The phytochemicals demonstrate direct bactericidal or bacteriostatic effects, such as: (i) prevention of bacterial adherence to mucosal surfaces of the pharynx, skin, and teeth surface; (ii) inhibition of glycolytic enzymes and pH drop; (iii) reduction of biofilm and plaque formation; and (iv) cell surface hydrophobicity. Collectively, findings from numerous studies suggest that phytochemicals could be used as drugs for elimination of infections with minimal side effects.

Indexed as

Bacterial AdhesionBacterial ProteinsBiofilmsDental CariesGene Expression Regulation, BacterialHumansHydrophobic and Hydrophilic InteractionsPharynxPhytochemicalsSkinStreptococcusBacterial ProteinsPhytochemicalsadherencebiofilmphytochemicalquorum sensingS. agalactiaeS. mutansS. pneumoniaeS. pyogenesstreptococci

Identifiers

PMID26901172
PMCPMC6273676
OpenAlexW2281770416

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.