Trial reportPloS one2016
Intermuscular Coherence in Normal Adults: Variability and Changes with Age.
Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Intramuscular coherence enables robust assessment of modulated supra-spinal input in human gait: an inter-dependence study of visual task and walking speed.Experimental brain research · 2023Trial
- Differences in Muscle Inter-Phasic Coherence During Side Kick Techniques Among Male Sanda Athletes of Different Skill Levels Based on Sensor Analysis: A Cross-Sectional Study.Sensors (Basel, Switzerland) · 2026Article
- Neuroengineering approaches assessing structural and functional changes of motor descending pathways in stroke.Progress in biomedical engineering (Bristol, England) · 2025Review
- Intermuscular coherence during arm movement changes significantly with shoulder abduction and age, but not with limb dominance.Frontiers in physiology · 2025Article
- Added load increases the peak frequency of intermuscular coherence.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2024Article
- Intermuscular coherence as an early biomarker for amyotrophic lateral sclerosis: The protocol for a prospective, multicenter study.PloS one · 2024Article
- Functional electrical stimulation therapy for upper extremity rehabilitation following spinal cord injury: a pilot study.Spinal cord series and cases · 2023Article
- Spectral properties of physiological mirror activity: an investigation of frequency features and common input between homologous muscles.Scientific reports · 2022Article
- Changes in intermuscular connectivity during active elbow extension reveal a functional simplification of motor control after stroke.Frontiers in neuroscience · 2022Article
- Intramuscular coherence during challenging walking in incomplete spinal cord injury: Reduced high-frequency coherence reflects impaired supra-spinal control.Frontiers in human neuroscience · 2022Article
- Intermuscular coherence between homologous muscles during dynamic and static movement periods of bipedal squatting.Journal of neurophysiology · 2020Article
- Modulation of Intermuscular Beta Coherence in Different Rhythmic Mandibular Behaviors.Frontiers in human neuroscience · 2020Article
- Lack of inter-muscular coherence of axial muscles in Pisa syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Article
- Amplitude cancellation influences the association between frequency components in the neural drive to muscle and the rectified EMG signal.PLoS computational biology · 2019Article
- Mills' syndrome revisited.Journal of neurology · 2019Review
- Decrease in force steadiness with aging is associated with increased power of the common but not independent input to motor neurons.Journal of neurophysiology · 2018Article
- Spasms after spinal cord injury show low-frequency intermuscular coherence.Journal of neurophysiology · 2018Article
- Coordination of plantar flexor muscles during bipedal and unipedal stances in young and elderly adults.Experimental brain research · 2018Article
- Abnormal Blink Reflex and Intermuscular Coherence in Writer's Cramp.Frontiers in neurology · 2018Article
- Aging and Strength Training Influence Knee Extensor Intermuscular Coherence During Low- and High-Force Isometric Contractions.Frontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
We investigated beta-band intermuscular coherence (IMC) in 92 healthy adults stratified by decade of age, and analysed variability between and within subjects. In the dominant upper limb, IMC was estimated between extensor digitorum communis and first dorsal interosseous as well as between flexor digitorum superficialis and first dorsal interosseous. In the ipsilateral lower limb, IMC was measured between medial gastrocnemius and extensor digitorum brevis as well as between tibialis anterior and extensor digitorum brevis. Age-related changes in IMC were analysed with age as a continuous variable or binned by decade. Intrasession variance of IMC was examined by dividing sessions into pairs of epochs and comparing coherence estimates between these pairs. Eight volunteers returned for a further session after one year, allowing us to compare intrasession and intersession variance. We found no age-related changes in IMC amplitude across almost six decades of age, allowing us to collate data from all ages into an aggregate normative dataset. Interindividual variability ranged over two orders of magnitude. Intrasession variance was significantly greater than expected from statistical variability alone, and intersession variance was even larger. Potential contributors include fluctuations in task performance, differences in electrode montage and short-term random variation in central coupling. These factors require further exploration and, where possible, minimisation. This study provides evidence that coherence is remarkably robust to senescent changes in the nervous system and provides a large normative dataset for future applications of IMC as a biomarker in disease states.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.