Evidence map›Paper›PMID 26901113›Full record

Trial reportPloS one2016

The Economic Burden Attributable to a Child's Inpatient Admission for Diarrheal Disease in Rwanda.

Fidele Ngabo, Mercy Mvundura, Lauren Gazley, Maurice Gatera, Celse Rugambwa, Eugene Kayonga, Yvette Tuyishime, Jeanne Niyibaho, Jason M Mwenda, Philippe Donnen and 3 more

Abstract readClinical Trial
In one paragraph

Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  13. Economic burden of childhood diarrhea in Burundi.Global health research and policy · 2021
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  17. Review
  18. Development and Evaluation of an iiPCR Assay forThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fidele NgaboUniversité Libre de Bruxelles, Ecole de Santé Publique, Brussels, Belgium.
Mercy MvunduraPATH, Devices and Tools Global Program, Seattle 98121, Washington, United States of America.
Lauren GazleyPATH, Vaccine Access and Delivery Global Program, Seattle 98121, Washington, United States of America.
Maurice GateraMinistry of Health, Rwanda Biomedical Center, Kigali, Rwanda.
Celse RugambwaWorld Health Organization, Rwanda Country Office, Kigali, Rwanda.
Eugene KayongaMinistry of Health, Rwanda Biomedical Center, Kigali, Rwanda.
Yvette TuyishimeMinistry of Health, Rwanda Biomedical Center, Kigali, Rwanda.
Jeanne NiyibahoMinistry of Health, Rwanda Biomedical Center, Kigali, Rwanda.
Jason M MwendaWorld Health Organization, Regional Office for Africa, Brazzaville, Republic of Congo.
Philippe DonnenUniversité Libre de Bruxelles, Ecole de Santé Publique, Brussels, Belgium.
Philippe LepageHôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium.
Agnes BinagwahoMinistry of Health, Kigali, Rwanda.
Deborah AtherlyPATH, Vaccine Access and Delivery Global Program, Seattle 98121, Washington, United States of America.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundDiarrhea is one of the leading causes of childhood morbidity and mortality. Hospitalization for diarrhea can pose a significant burden to health systems and households. The objective of this study was to estimate the economic burden attributable to hospitalization for diarrhea among children less than five years old in Rwanda. These data can be used by decision-makers to assess the impact of interventions that reduce diarrhea morbidity, including rotavirus vaccine introduction.

methodsThis was a prospective costing study where medical records and hospital bills for children admitted with diarrhea at three hospitals were collected to estimate resource use and costs. Hospital length of stay was calculated from medical records. Costs incurred during the hospitalization were abstracted from the hospital bills. Interviews with the child's caregivers provided data to estimate household costs which included transport costs and lost income. The portion of medical costs borne by insurance and household were reported separately. Annual economic burden before and after rotavirus vaccine introduction was estimated by multiplying the reported number of diarrhea hospitalizations in public health centers and district hospitals by the estimated economic burden per hospitalization. All costs are presented in 2014 US$.

resultsCosts for 203 children were analyzed. Approximately 93% of the children had health insurance coverage. Average hospital length of stay was 5.3 ± 3.9 days. Average medical costs for each child for the illness resulting in a hospitalization were $44.22 ± $23.74 and the total economic burden was $101, of which 65% was borne by the household. For households in the lowest income quintile, the household costs were 110% of their monthly income. The annual economic burden to Rwanda attributable to diarrhea hospitalizations ranged from $1.3 million to $1.7 million before rotavirus vaccine introduction.

conclusionHouseholds often bear the largest share of the economic burden attributable to diarrhea hospitalization and the burden can be substantial, especially for households in the lowest income quintile.

Indexed as

Cost of IllnessDatabases, FactualChildChild, PreschoolCosts and Cost AnalysisDiarrheaFemaleHumansInfantInsurance CoverageMalePatient AdmissionProspective StudiesRotavirus InfectionsRotavirus VaccinesRwandaRotavirus Vaccines

Identifiers

PMID26901113
PMCPMC4764684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.