Evidence map›Paper›PMID 26900799›Full record

ArticleHuman vaccines & immunotherapeutics2016

A preliminary cost-effectiveness analysis of hepatitis E vaccination among pregnant women in epidemic regions.

Yueyuan Zhao, Xuefeng Zhang, Fengcai Zhu, Hui Jin, Bei Wang

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. [Vaccines against hepatitis E virus: state of development].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Review
  7. Viral hepatitis and pregnancy.Nature reviews. Gastroenterology & hepatology · 2021
    Review
  8. Review
  9. Review
  10. Article
  11. Hepatitis E: Update on Prevention and Control.BioMed research international · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yueyuan Zhaoa School of Public Health, Southeast University , Nanjing , China.
Xuefeng Zhangb Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , China.
Fengcai Zhub Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , China.
Hui Jina School of Public Health, Southeast University , Nanjing , China.
Bei Wanga School of Public Health, Southeast University , Nanjing , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective To estimate the cost-effectiveness of hepatitis E vaccination among pregnant women in epidemic regions. Methods A decision tree model was constructed to evaluate the cost-effectiveness of 3 hepatitis E virus vaccination strategies from societal perspectives. The model parameters were estimated on the basis of published studies and experts' experience. Sensitivity analysis was used to evaluate the uncertainties of the model. Results Vaccination was more economically effective on the basis of the incremental cost-effectiveness ratio (ICER< 3 times China's per capital gross domestic product/quality-adjusted life years); moreover, screening and vaccination had higher QALYs and lower costs compared with universal vaccination. No parameters significantly impacted ICER in one-way sensitivity analysis, and probabilistic sensitivity analysis also showed screening and vaccination to be the dominant strategy. Conclusion Screening and vaccination is the most economical strategy for pregnant women in epidemic regions; however, further studies are necessary to confirm the efficacy and safety of the hepatitis E vaccines.

Indexed as

Cost-Benefit AnalysisChinaCohort StudiesEpidemicsFemaleHepatitis EHumansPregnancyPregnancy Complications, InfectiousVaccinationViral VaccinesViral Vaccinescost-effectiveness analysisdecision tree modelhepatitis E vaccinespregnant women

Identifiers

PMID26900799
PMCPMC4994743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.