Evidence map›Paper›PMID 26900574›Full record

ArticleThe journal of prevention of Alzheimer's disease2016

Dietary Factors and Cognitive Decline.

P J Smith, J A Blumenthal

Abstract read
In one paragraph

Article in The journal of prevention of Alzheimer's disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P J SmithDepartment of Psychiatry and Behavioral Sciences at Duke University Medical Center, Durham, USA.
J A BlumenthalDepartment of Psychiatry and Behavioral Sciences at Duke University Medical Center, Durham, USA.

Funding

Facility and Web-based Approaches to Lifestyle Change in Resistant HypertensionR01HL122836 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A, SHERWOOD, ANDREW · 2015 to 2019
$4.2M
Lifestyle, CVD Risk and Cognitive ImpairmentR01HL109219 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A · 2011 to 2015
$4.1M
NHLBI NIH HHS R01 HL109219NHLBI NIH HHS R01 HL122836
6 · The paper itself

Abstract

Cognitive decline is an increasingly important public health problem, with more than 100 million adults worldwide projected to develop dementia by 2050. Accordingly, there has been an increased interest in preventive strategies that diminish this risk. It has been recognized that lifestyle factors including dietary patterns, may be important in the prevention of cognitive decline and dementia in later life. Several dietary components have been examined, including antioxidants, fatty acids, and B vitamins. In addition, whole dietary eating plans, including the Mediterranean diet (MeDi), and the Dietary Approaches to Stop Hypertension (DASH) diet, with and without weight loss, have become areas of increasing interest. Although prospective epidemiological studies have observed that antioxidants, fatty acids, and B vitamins are associated with better cognitive functioning, randomized clinical trials have generally failed to confirm the value of any specific dietary component in improving neurocognition. Several randomized trials have examined the impact of changing 'whole' diets on cognitive outcomes. The MeDi and DASH diets offer promising preliminary results, but data are limited and more research in this area is needed.

Indexed as

cognitive functiondementiaDietary patternsnutrition

Identifiers

PMID26900574
PMCPMC4758517

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.