ArticleACS macro letters2015
ATRP Synthesis of Sunflower Polymers using Cyclic Multimacroinitiators.
Article in ACS macro letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed.
- Beyond Lipids: Exploring Advances in Polymeric Gene Delivery in the Lipid Nanoparticles Era.Advanced materials (Deerfield Beach, Fla.) · 2024Review
- Synthesis of stimuli-responsive nanosized ring-like colloids and cyclic polymersChemical science · 2019Article
- Dual Polymerizations: Untapped Potential for Biomaterials.Advanced healthcare materials · 2019Review
- Design and Synthesis of a Cyclic Double-Grafted Polymer Using Active Ester Chemistry and Click Chemistry via A "Grafting onto" Method.Polymers · 2019Article
- Brush-First and ROMP-Out with Functional (Macro)monomers: Method Development, Structural Investigations, and Applications of an Expanded Brush-Arm Star Polymer Platform.Macromolecules · 2018Article
- Synthesis and Phase Transition of Poly(N-isopropylacrylamide)-Based Thermo-Sensitive Cyclic Brush Polymer.Polymers · 2017Article
- Nano-Sized Sunflower Polycations As Effective Gene Transfer Vehicles.Small (Weinheim an der Bergstrasse, Germany) · 2016Article
- Cyclic Graft Copolymer Unimolecular Micelles: Effects of Cyclization on Particle Morphology and Thermoresponsive Behavior.Macromolecules · 2016Article
- Sunflower Polymers for Folate-Mediated Drug Delivery.Biomacromolecules · 2016Article
- Polymer nanostructures synthesized by controlled living polymerization for tumor-targeted drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2015Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Polymers with advanced architectures can now be readily and reproducibly synthesized using controlled living polymerization. These materials are attractive as potential drug carriers due to their tunable size, versatile methods of drug incorporation and release, and ease of functionalization with targeting ligands. In this work, we report the design and development of macrocyclic brush, or "sunflower," polymers, synthesized by controlled radical polymerization of hydrophilic "petals" from a cyclic multimacroinitiator "core." These nanostructures can be synthesized with low polydispersity and controlled sizes depending on polymerization time. We further demonstrate that folate-functionalized sunflower polymers facilitate receptor-mediated uptake into cancer cells. These materials therefore show potential as drug carriers for anti-cancer therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.