Evidence map›Paper›PMID 26900391›Full record

ReviewNutrition & metabolism2016

Probiotics in prevention and treatment of obesity: a critical view.

Nazarii Kobyliak, Caterina Conte, Giovanni Cammarota, Andreana P Haley, Igor Styriak, Ludovit Gaspar, Jozef Fusek, Luis Rodrigo, Peter Kruzliak

Open access · goldAbstract readReview
In one paragraph

Review in Nutrition & metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 3 pooled it
19.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 3 syntheses or guidelines pooled it, 340 citations in OpenAlex.

  1. ProbioticNarra J · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Effect of probioticWorld journal of gastroenterology · 2021
    Trial
  9. Trial
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Unveiling the probiotic potential ofAIMS microbiology · 2026
    Article
  16. Article
  17. Nutrients · 2025
    Article
  18. Article
  19. Microbial Biotransformation of Chicory byInternational journal of molecular sciences · 2025
    Article
  20. Review

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Nazarii KobyliakDivision of Endocrinology and Metabolic Diseases, Catholic University of Sacred Heart, A. Gemelli Medical School, Rome, Italy.
Caterina ConteDivision of Endocrinology and Metabolic Diseases, Catholic University of Sacred Heart, A. Gemelli Medical School, Rome, Italy.
Giovanni CammarotaDivision of Internal Medicine and Gastroenterology, Catholic University of Sacred Heart, A. Gemelli Medical School, Rome, Italy.
Andreana P HaleyDepartment of Psychology, The University of Texas at Austin, Austin, TX USA ; University of Texas Imaging Research Center, Austin, TX USA.
Igor StyriakInstitute of Geotechnics, Department of Biotechnology, Slovak Academy of Sciences, Kosice, Slovak Republic.
Ludovit Gaspar2nd Department of Internal Medicine, Comenius University and University Hospital, Mickiewiczova 13, 813 69 Bratislava, Slovak Republic.
Jozef FusekFaculty of Health Studies, University of Pardubice, Pardubice, Czech Republic.
Luis RodrigoDepartment of Gastroenterology, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
Peter KruzliakDepartment of Gastroenterology, Central University Hospital of Asturias (HUCA), Oviedo, Spain ; 2nd Department of Internal Medicine, Faculty of Medicine, Masaryk University, Pekarska 53, 656 91 Brno, Czech Republic ; Laboratory of Structural Biology and Proteomics, Central Laboratories, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic.
Università Cattolica del Sacro Cuore · ITHospital Universitario Central de Asturias · ESComenius University Bratislava · SKSlovak Academy of Sciences · SKThe University of Texas at Austin · USUniversity of Pardubice · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worldwide prevalence of obesity more than doubled between 1980 and 2014. The obesity pandemic is tightly linked to an increase in energy availability, sedentariness and greater control of ambient temperature that have paralleled the socioeconomic development of the past decades. The most frequent cause which leads to the obesity development is a dysbalance between energy intake and energy expenditure. The gut microbiota as an environmental factor which influence whole-body metabolism by affecting energy balance but also inflammation and gut barrier function, integrate peripheral and central food intake regulatory signals and thereby increase body weight. Probiotics have physiologic functions that contribute to the health of gut microbiota, can affect food intake and appetite, body weight and composition and metabolic functions through gastrointestinal pathways and modulation of the gut bacterial community.

Indexed as

Gut microbiotaIntestinal microfloraObesityPreventionProbioticsTreatment

Identifiers

PMID26900391
PMCPMC4761174
OpenAlexW2285227042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.