Evidence map›Paper›PMID 26900362›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Vemurafenib and concomitant stereotactic radiation for the treatment of melanoma with spinal metastases: A case report.

Dinu Stefan, Hosni Popotte, Andreea Raluca Stefan, Audrey Tesniere, Aurélie Tomaszewski, Paul Lesueur, Jean-Louis Habrand, Laurence Verneuil

Abstract readCase Reports
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dinu StefanDepartment of Radiotherapy, François Baclesse Cancer Center, 3 Avenue General Harris, F-14000 Caen, France.
Hosni PopotteDepartment of Radiotherapy, François Baclesse Cancer Center, 3 Avenue General Harris, F-14000 Caen, France.
Andreea Raluca StefanCHU-Caen, Dermatology, F-14033 Caen, France; Université-Caen-Basse-Normandie, Medical-School-Caen, F-14000, France.
Audrey TesniereCHU-Caen, Dermatology, F-14033 Caen, France; Université-Caen-Basse-Normandie, Medical-School-Caen, F-14000, France.
Aurélie TomaszewskiDepartment of Radiotherapy, François Baclesse Cancer Center, 3 Avenue General Harris, F-14000 Caen, France.
Paul LesueurDepartment of Radiotherapy, François Baclesse Cancer Center, 3 Avenue General Harris, F-14000 Caen, France.
Jean-Louis HabrandDepartment of Radiotherapy, François Baclesse Cancer Center, 3 Avenue General Harris, F-14000 Caen, France.
Laurence VerneuilCHU-Caen, Dermatology, F-14033 Caen, France; Université-Caen-Basse-Normandie, Medical-School-Caen, F-14000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 56-year-old man with BRAFV600E melanoma and spinal metastases treated with vemurafenib and stereotactic radiation showed a partial response without neurological, skin or mucosal toxicity, 8 months after completion of this combination. This case suggests that stereotactic radiation spares normal tissues and might be safer than conventional fractionated radiation with vemurafenib.

Indexed as

Melanoma metastasisStereotactic radiationVemurafenib

Identifiers

PMID26900362
PMCPMC4716399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.