Evidence map›Paper›PMID 26900289›Full record

ReviewWorld journal of gastroenterology2016

Hepatitis E virus: An ancient hidden enemy in Latin America.

Nora A Fierro, Mauricio Realpe, Tzintli Meraz-Medina, Sonia Roman, Arturo Panduro

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. The Role of Glutathione in Selected Viral Diseases.Antioxidants (Basel, Switzerland) · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Challenges in research and management of hepatitis E virus infection in Cuba, Mexico, and Uruguay.Revista panamericana de salud publica = Pan American journal of public health · 2018
    Article
  13. Hepatitis E: Update on Prevention and Control.BioMed research international · 2018
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Epidemiology of hepatitis E virus in Iran.World journal of gastroenterology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nora A FierroNora A Fierro, Immunovirology Unit, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Department of Physiology, Health Sciences Center, University of Guadalajara, Guadalajara 44280, Jalisco, México.
Mauricio RealpeNora A Fierro, Immunovirology Unit, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Department of Physiology, Health Sciences Center, University of Guadalajara, Guadalajara 44280, Jalisco, México.
Tzintli Meraz-MedinaNora A Fierro, Immunovirology Unit, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Department of Physiology, Health Sciences Center, University of Guadalajara, Guadalajara 44280, Jalisco, México.
Sonia RomanNora A Fierro, Immunovirology Unit, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Department of Physiology, Health Sciences Center, University of Guadalajara, Guadalajara 44280, Jalisco, México.
Arturo PanduroNora A Fierro, Immunovirology Unit, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Department of Physiology, Health Sciences Center, University of Guadalajara, Guadalajara 44280, Jalisco, México.
Hospital Civil de Guadalajara · MXUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) infection is a common cause of acute clinical hepatitis worldwide. HEV is an RNA-containing virus and the only member of the genus Hepevirus in the family Hepeviridae. Human HEV is classified into four genotypes widely distributed across the world. The virus is mainly transmitted via the fecal-oral route, and water-borne epidemics have become characteristic of hepatitis E in developing countries, including those in Latin America. The zoonotic potential of HEV is broadly recognized. Thus, there is an urgent need to re-evaluate virus transmission scenarios and to enforce epidemiological surveillance systems. Additionally, it is known that HEV infections, initially defined as self-limiting, can also take chronic courses in immunocompromised patients. Moreover, we recently reported a high seroprevalence of HEV in samples from cirrhotic patients with no other etiological agents present, suggesting the potential role of HEV in the development of chronic liver illness. In this review, HEV genomic variability, transmission, chronic infectious course, zoonotic potential and treatment are discussed. Focus is placed on the impact of HEV infection in Latin America, to support the development of specific control strategies and the handling of this important and typically imperceptible viral infection.

Indexed as

AnimalsAntiviral AgentsGenetic VariationGenotypeHepatitis, ChronicHepatitis EHepatitis E virusHumansLatin AmericaRisk FactorsTreatment OutcomeZoonosesAntiviral AgentsEmerging diseasesHepatitis E virus-chronic infectionMexicoViral genotypesZoonosis

Identifiers

PMID26900289
PMCPMC4735001
OpenAlexW2418057701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.