Evidence map›Paper›PMID 26900274›Full record

ReviewJournal of clinical and experimental hepatology2015

Magnetic Resonance Spectroscopy: Principles and Techniques: Lessons for Clinicians.

Joshua M Tognarelli, Mahvish Dawood, Mohamed I F Shariff, Vijay P B Grover, Mary M E Crossey, I Jane Cox, Simon D Taylor-Robinson, Mark J W McPhail

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical and experimental hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.

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  10. The Development of Neural Inhibition across Species: Insights from the Hurst Exponent.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joshua M TognarelliLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
Mahvish DawoodLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
Mohamed I F ShariffLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
Vijay P B GroverLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
Mary M E CrosseyLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
I Jane CoxThe Foundation for Liver Research, Institute of Hepatology, 69-75 Chenies Mews, London WC1E 6HX, United Kingdom.
Simon D Taylor-RobinsonLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
Mark J W McPhailLiver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.
Imperial College London · GBFoundation for Liver Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance spectroscopy (MRS) provides a non-invasive 'window' on biochemical processes within the body. Its use is no longer restricted to the field of research, with applications in clinical practice increasingly common. MRS can be conducted at high magnetic field strengths (typically 11-14 T) on body fluids, cell extracts and tissue samples, with new developments in whole-body magnetic resonance imaging (MRI) allowing clinical MRS at the end of a standard MRI examination, obtaining functional information in addition to anatomical information. We discuss the background physics the busy clinician needs to know before considering using the technique as an investigative tool. Some potential applications of hepatic and cerebral MRS in chronic liver disease are also discussed.

Indexed as

CPMG, Carr-Purcell-Meiboom-Gill sequenceCSI, chemical shift imagingFID, free induction decayKEGG, Kyoto Encyclopedia for Genes and GenomesK, Kelvinmagnetic resonance imagingmagnetic resonance spectroscopymetabolomicsMRI, magnetic resonance imagingMR, magnetic resonanceMRS, magnetic resonance spectroscopyMSEA, metabolite set enrichment analysisNMR, nuclear magnetic resonanceNOESY, nuclear Overhauser enhancement spectroscopynuclear magnetic resonancePCA, principal components analysisPC, principal componentsPLS-DA, partial least squared discriminant analysisPRESS, point-resolved spectroscopySTEAM, stimulated echo acquisition modeT1, spin-lattice relaxationT2, spin-spin relaxationTE, echo timeTMAO, trimethylamine N-oxideTR, repetition timeT, Tesla

Identifiers

PMID26900274
PMCPMC4723643
OpenAlexW2172825401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.