Evidence map›Paper›PMID 26900147›Full record

SynthesisScientific reports2016

Nighttime sleep duration, 24-hour sleep duration and risk of all-cause mortality among adults: a meta-analysis of prospective cohort studies.

Xiaoli Shen, Yili Wu, Dongfeng Zhang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Sleep duration and health outcomes: an umbrella review.Sleep & breathing = Schlaf & Atmung · 2022
    Pooled it
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  9. Trial
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  11. Article
  12. Review
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  15. Article
  16. Lifestyle Medicine and Cardiovascular Health.American journal of lifestyle medicine · 2026
    Review
  17. Article
  18. Article
  19. Sleep Patterns and Human Brain Health.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025
    Review
  20. Association between sleep duration and obesity in patients with type 2 diabetes: A longitudinal study.Diabetic medicine : a journal of the British Diabetic Association · 2025
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoli ShenDepartment of Epidemiology and Health Statistics, Medical College of Qingdao University, Shandong, Qingdao 266021, Dongzhou Road, No.38, P.R. China.
Yili WuDepartment of Epidemiology and Health Statistics, Medical College of Qingdao University, Shandong, Qingdao 266021, Dongzhou Road, No.38, P.R. China.
Dongfeng ZhangDepartment of Epidemiology and Health Statistics, Medical College of Qingdao University, Shandong, Qingdao 266021, Dongzhou Road, No.38, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A dose-response meta-analysis was conducted to summarize evidence from prospective cohort studies about the association of nighttime sleep duration and 24-hour sleep duration with risk of all-cause mortality among adults. Pertinent studies were identified by a search of Embase and PubMed databases to March 2015. A two-stage random-effects dose-response meta-analysis was used to combine study-specific relative risks and 95% confidence intervals [RRs (95% CIs)]. Thirty-five articles were included. Compared with 7 hours/day, the RRs (95% CIs) of all-cause mortality were 1.07 (1.03-1.13), 1.04 (1.01-1.07), 1.01 (1.00-1.02), 1.07 (1.06-1.09), 1.21 (1.18-1.24), 1.37 (1.32-1.42) and 1.55 (1.47-1.63) for 4, 5, 6, 8, 9, 10 and 11 hours/day of nighttime sleep, respectively (146,830 death cases among 1,526,609 participants), and the risks were 1.09 (1.04-1.14), 1.05 (1.02-1.09), 1.02 (1.00-1.03), 1.08 (1.05-1.10), 1.27 (1.20-1.36), 1.53 (1.38-1.70) and 1.84 (1.59-2.13) for 4, 5, 6, 8, 9, 10 and 11 hours/day of 24-hour sleep, respectively (101,641 death cases among 903,727 participants). The above relationships were also found in subjects without cardiovascular diseases and cancer at baseline, and other covariates did not influence the relationships substantially. The results suggested that 7 hours/day of sleep duration should be recommended to prevent premature death among adults.

Indexed as

Cause of DeathAdultCardiovascular DiseasesHumansNeoplasmsProspective StudiesRisk FactorsSleep

Identifiers

PMID26900147
PMCPMC4761879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.