Evidence map›Paper›PMID 26900038›Full record

ArticleLasers in surgery and medicine2017

Computer simulations of thermal tissue remodeling during transvaginal and transurethral laser treatment of female stress urinary incontinence.

Luke A Hardy, Chun-Hung Chang, Erinn M Myers, Michael J Kennelly, Nathaniel M Fried

Abstract read
In one paragraph

Article in Lasers in surgery and medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Transurethral high-intensity ultrasound for treatment of stress urinary incontinence (SUI): simulation studies with patient-specific models.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2018
    Article
  9. LASER PROBE WITH INTEGRATED CONTACT COOLING FOR SUBSURFACE TISSUE THERMAL REMODELING.Journal of the Mississippi Academy of Sciences. Mississippi Academy of Sciences · 2018
    Article
  10. Article
  11. Optical Clearing of Vaginal Tissues in Cadavers.Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Luke A HardyDepartment of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina.
Chun-Hung ChangDepartment of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina.
Erinn M MyersMcKay Department of Urology, Carolinas Medical Center, Charlotte, North Carolina.
Michael J KennellyMcKay Department of Urology, Carolinas Medical Center, Charlotte, North Carolina.
Nathaniel M FriedDepartment of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina.
University of North Carolina at Charlotte · USCarolinas Medical Center · US

Funding

Minimally Invasive Laser Treatment of Female Stress Urinary IncontinenceR15DK099774 · NIDDK · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI FRIED, NATHANIEL M · 2014 to 2014
$434k
NIDDK NIH HHS R15 DK099774
6 · The paper itself

Abstract

BACKGROUND AND

objectivesA non-surgical method is being developed for treating female stress urinary incontinence by laser thermal remodeling of subsurface tissues with applied surface tissue cooling. Computer simulations of light transport, heat transfer, and thermal damage in tissue were performed, comparing transvaginal and transurethral approaches. STUDY DESIGN/MATERIALS AND

methodsMonte Carlo (MC) simulations provided spatial distributions of absorbed photons in the tissue layers (vaginal wall, endopelvic fascia, and urethral wall). Optical properties (n,μ

resultsFor the transvaginal approach, 37% of energy was absorbed in the endopelvic fascia target layer with 0.8% deposited beyond it. Peak temperature was 71°C, the treatment zone was 0.8-mm-diameter, and 2.4 mm of the 2.7-mm-thick vaginal wall was preserved. For transurethral approach, 18% energy was absorbed in endopelvic fascia with 0.3% deposited beyond the layer. Peak temperature was 80°C, treatment zone was 2.0-mm-diameter, and 0.6 mm of 2.4-mm-thick urethral wall was preserved.

conclusionsComputer simulations suggest that transvaginal approach is more feasible than transurethral approach. Lasers Surg. Med. 49:198-205, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

Computer SimulationFasciaFemaleHumansLaser TherapyModels, BiologicalMonte Carlo MethodUrethraUrinary Incontinence, StressVaginacoagulationincontinencelaserMonte Carlosimulationsthermal remodeling

Identifiers

PMID26900038
PMCPMC6095190
OpenAlexW2275414823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.