Evidence map›Paper›PMID 26899785›Full record

ArticleNeuroImage2016

A ventral salience network in the macaque brain.

Alexandra Touroutoglou, Eliza Bliss-Moreau, Jiahe Zhang, Dante Mantini, Wim Vanduffel, Bradford C Dickerson, Lisa Feldman Barrett

Open access · greenAbstract read
In one paragraph

Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cellular basis for cortical network aging in primates.bioRxiv : the preprint server for biology · 2025
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  7. Translation of monosynaptic circuits underlying amygdala fMRI neurofeedback training.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  8. What can neuroimaging of neuromodulation reveal about the basis of circuit therapies for psychiatry?Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  9. Evolutionarily conserved neural responses to affective touch in monkeys transcend consciousness and change with age.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Intrinsic functional clustering of the macaque insular cortex.Frontiers in integrative neuroscience · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Alexandra Touroutoglou *Department of Neurology, Massachusetts General Hospital/Harvard Medical School 02114.
Eliza Bliss-Moreau *California National Primate Research Center, Davis, California 95616.
Jiahe Zhang *Northeastern University, Boston, Massachusetts 02115.
Dante MantiniLaboratory for Neuro- and Psychophysiology, Department of Neurosciences, KU Leuven, 3000 Leuven, Belgium.
Wim VanduffelAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, MA 02129.
Bradford C DickersonDepartment of Neurology, Massachusetts General Hospital/Harvard Medical School 02114.
Lisa Feldman BarrettAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, MA 02129.
Massachusetts General Hospital · USAthinoula A. Martinos Center for Biomedical Imaging · USHarvard University · USNortheastern University · USUniversity of California, Davis · USUniversity of Oxford · GB

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Neural Mechanisms of Social Decision Making in AgingR01AG030311 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI BARRETT, LISA FELDMAN, DICKERSON, BRADFORD C · 2006 to 2016
$5.6M
NIA NIH HHS R01 AG030311NIH HHS P51 OD011107Wellcome Trust
6 · The paper itself

Abstract

Successful navigation of the environment requires attending and responding efficiently to objects and conspecifics with the potential to benefit or harm (i.e., that have value). In humans, this function is subserved by a distributed large-scale neural network called the "salience network". We have recently demonstrated that there are two anatomically and functionally dissociable salience networks anchored in the dorsal and ventral portions of the human anterior insula (Touroutoglou et al., 2012). In this paper, we test the hypothesis that these two subnetworks exist in rhesus macaques (Macaca mulatta). We provide evidence that a homologous ventral salience network exists in macaques, but that the connectivity of the dorsal anterior insula in macaques is not sufficiently developed as a dorsal salience network. The evolutionary implications of these finding are considered.

Indexed as

AnimalsAttentionBrainBrain MappingCerebral CortexFemaleMacaca mulattaMagnetic Resonance ImagingMaleNeural PathwaysSpecies SpecificityIntrinsic functional connectivityResting state fMRIRhesus macaquesSalience network

Identifiers

PMID26899785
PMCPMC4851897
OpenAlexW2282994271

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.