ArticleJournal of clinical immunology2016
Primary Immunodeficiency Diseases in Aguascalientes, Mexico: Results from an Educational Program.
Article in Journal of clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Awareness of primary immunodeficiency diseases at a national pediatric reference center in Peru.Einstein (Sao Paulo, Brazil) · 2021Article
- Article
- The impact of combining educational program with the improving of infrastructure to diagnose on early detection of primary immunodeficiencies in children.Immunologic research · 2019Article
- Disease burden for patients with primary immunodeficiency diseases identified at reference hospitals in Guanajuato, Mexico.PloS one · 2017Article
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Authors and funding
11 authors.
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Abstract
purposePrimary immunodeficiencies (PIDs) are a heterogeneous group of disorders characterized mainly by recurrent infections. Late diagnosis remains as one of the main issues to solve. We aimed to increase PID diagnosis in Aguascalientes, a 1.3 million inhabitants state in the center of Mexico, and to describe the clinical features of such patients.
methodsWe developed an educational program for health personnel and general public; patients with possible PID were referred to a State University clinical center from December 2011 to December 2012. The patients were evaluated at the clinic and their definitive diagnosis pursued through laboratory, molecular and genetic assays. We describe the findings of those patients and analyze the impact of the program in terms of number of referrals.
resultsAfter 41 talks and 12 media appearances 151 patients were referred for evaluation. Fifteen (9.9%) were diagnosed with PID: five (33%) had antibody deficiencies, seven (47%) Well-defined syndromes, two (13%) Severe combined Immunodeficiency (SCID) and one case (7%) of an innate immune deficiency. All of the 15 PID patients had been referred by physicians, as opposed to the public. We estimated a "number needed to teach" of 75 physicians to get one PID patient referral.
conclusionEducational programs are a fundamental part of the global efforts to increase PID diagnosis and care. To be successful, such programs should include public relations, reach for first-contact physicians, and aim to develop an efficient referral network with molecular diagnostic capability. Enhancing medical knowledge on PID is a successful strategy to improve early diagnosis and treatment.
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