Evidence map›Paper›PMID 26897753›Full record

ArticleCerebellum (London, England)2017

Combined Cerebellar Proton MR Spectroscopy and DWI Study of Patients with Friedreich's Ataxia.

Laura Ludovica Gramegna, Caterina Tonon, David Neil Manners, Antonella Pini, Rita Rinaldi, Stefano Zanigni, Claudio Bianchini, Stefania Evangelisti, Filippo Fortuna, Valerio Carelli and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Cerebellum (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Multiway sparse distance weighted discrimination.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Laura Ludovica GramegnaFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Caterina TononFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy. caterina.tonon@unibo.it.
David Neil MannersFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Antonella PiniChild Neurology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, Bologna, Italy.
Rita RinaldiNeurology Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Stefano ZanigniFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Claudio BianchiniFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Stefania EvangelistiFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Filippo FortunaDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna , Bologna, Italy.
Valerio CarelliDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna , Bologna, Italy.
Claudia TestaFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Raffaele LodiFunctional MR Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
University of Bologna · ITPoliclinico S.Orsola-Malpighi · ITIstituto delle Scienze Neurologiche di Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Friedreich's ataxia (FRDA) is the commonest autosomal recessive ataxia, caused by GAA triplet expansion in the frataxin gene. Neuropathological studies in FRDA demonstrate that besides the primary neurodegeneration of the dorsal root ganglia, there is a progressive atrophy of the cerebellar dentate nucleus. Diffusion-weighted imaging (DWI) detected microstructural alterations in the cerebellum of FRDA patients. To investigate the biochemical basis of these alterations, we used both DWI and proton MR spectroscopy (

Indexed as

Diffusion Magnetic Resonance ImagingProton Magnetic Resonance SpectroscopyAdolescentAdultAspartic AcidCerebellumChildCholineFemaleFriedreich AtaxiaHumansLinear ModelsMaleMiddle AgedNeuroprotective AgentsSeverity of Illness IndexAspartic AcidCholineidebenoneN-acetylaspartateNeuroprotective AgentsUbiquinoneDWIFRDAProton MRS

Identifiers

PMID26897753
OpenAlexW2275107318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.