ArticleImplementation science : IS2016
Collaborative research and the co-production of knowledge for practice: an illustrative case study.
Article in Implementation science : IS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03699137 (Use and Impact of the Pre-hospital 12-lead Electrocardiogram in the Primary PCI Era), which is not on this map. Cited by 79 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use and Impact of the Pre-hospital 12-lead Electrocardiogram in the Primary PCI Era: Mixed Methods Study (PHECG2)
Who cites it
79 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The use of co-production, co-design and co-creation to mobilise knowledge in the management of health conditions: a systematic review.BMC health services research · 2022Pooled it
- Learning from the emergence of NIHR Collaborations for Leadership in Applied Health Research and Care (CLAHRCs): a systematic review of evaluations.Implementation science : IS · 2018Pooled it
- Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT.Health technology assessment (Winchester, England) · 2023Trial
- Strategies for research engagement of clinicians in allied health (STRETCH): a mixed methods research protocol.BMJ open · 2017Trial
- Let's Co! The how-to of working within a co-production framework to devise, design and execute collaborative multisite clinical trials.The British journal of clinical psychology · 2026Article
- Evaluation of Co-Production in Adolescent Health Research: A Mixed Methods Study From Born in Bradford.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Participatory development of innovation and implementation strategy - an action-oriented approach.BMC health services research · 2026Article
- SOARNet: Establishing an older adult focused practice-based research network.Journal of clinical and translational science · 2026Article
- Co-designing Nova Sleepcare: identifying priority areas for implementation.Frontiers in pediatrics · 2026Article
- Co-Creation Study Protocol for Developing a Nurse-Led Intervention to Deprescribe Benzodiazepines and Z-Hypnotics in Primary Care Aimed at Empowering Women.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- How does integrated knowledge translation work? A realist review.Health research policy and systems · 2025Review
- Developing a role for patients and the public in the implementation of health and social care research evidence into practice: the PIPER study (Pathways to Implementation for Public Engagement in Research) realist evaluation protocol.Research involvement and engagement · 2025Review
- Extending from Adaptation to Resilience Pathways: Perspectives from the Conceptual Framework to Key Insights.Environmental management · 2025Article
- Addressing power imbalance in research: exploring power in integrated knowledge translation health research.Research involvement and engagement · 2025Review
- A Web-Based Training Program for School Staff to Respond to Self-Harm: Design and Development of the Supportive Response to Self-Harm Program.JMIR formative research · 2024Article
- Identifying strategies and related principles supporting a co-design approach in an assistive device service delivery and research platform.Frontiers in rehabilitation sciences · 2024Article
- "We all see things through a different lens based on our life experiences": co-production of a web-based implementation toolkit with stakeholders across the health and social care system.Frontiers in health services · 2024Article
- A virtuous cycle of co-production: Reflections from a community priority-setting exercise.Health expectations : an international journal of public participation in health care and health policy · 2023Article
- Development of the Preferred Components for Co-Design in Research Guideline and Checklist: Protocol for a Scoping Review and a Modified Delphi Process.JMIR research protocols · 2023Article
- Tapping into the power of coproduction and knowledge mobilisation: Exploration of a facilitated interactive group learning approach to support equity-sensitive decision-making in local health and care services.Health expectations : an international journal of public participation in health care and health policy · 2023Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2008, the National Institute for Health Research (NIHR) began funding a major 5-year pilot research programme of translational research in England, establishing nine 'Collaborations for Leadership in Applied Health Research and Care' (CLAHRCs). A number of evaluations were carried out to examine whether or not the various collaborations worked as intended and why. In this paper, we examine what the theory of co-production adds to understanding of processes of knowledge creation and translation we observed in one of the CLAHRCs.
methodsA case study of a successful knowledge translation project was identified from our wider realist evaluation of the mechanisms of closer collaboration at play in the CLAHRC. In the project, a computer simulation model of an emergency pathway for acute ischaemic stroke was built to explore if and how the time between the onset and treatment of the condition could be minimised by redesigning the pathway. The aim of the case study was to improve our understanding of the nature and workings of the mechanisms of closer collaboration that were associated with the more successful projects by examining the relevance of the theory of co-production. Qualitative methods of analysis were used to explore the fit between the mechanisms of closer collaboration we observed in the realist evaluation and the principles of co-production we identified from the literature.
resultsWe found a close fit between the nine mechanisms of closer collaboration at work in the project and the principles of co-production (active agents; equality of partners; reciprocity and mutuality; transformative; and facilitated). The successful style of collaborative working exemplified by the project was consistent with a strong form of co-production.
conclusionsIn our view, the theory of co-production provides useful insights into what it is about the qualities of collaborative working that inspire the requisite mechanisms for generating knowledge that is translated into practice. The theory provides a potentially useful basis for future knowledge translation programmes and projects in applied health research in a range of contexts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.