ArticleJournal of ophthalmic inflammation and infection2016
Microbiological profiles of fungal keratitis: a 10-year study at a tertiary referral center.
Article in Journal of ophthalmic inflammation and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- From trauma to brain:IDCases · 2026Article
- Clinical features, microbiological characteristics, and treatment outcomes of fungal keratitis in a tertiary referral hospital in Eastern China.BMC infectious diseases · 2025Article
- Clinical Characteristics and In Vivo Confocal Microscopic Study in Candida Keratitis.Translational vision science & technology · 2025Article
- Resistance trend in bacteria isolated from corneal ulcers: A retrospective analysis from Pakistan.PloS one · 2025Article
- Long-Term Prevalence of Fungal Keratitis at a Swiss Tertiary Eye Clinic.Microorganisms · 2024Article
- Characteristics of In Vitro Culture and In Vivo Confocal Microscopy in Patients with Fungal Keratitis in a Tertiary Referral Hospital in Central China.Microorganisms · 2023Article
- Fungal keratitis in Iran: Risk factors, clinical features, and mycological profile.Frontiers in cellular and infection microbiology · 2023Article
- The Case for Fungal Keratitis to Be Accepted as a Neglected Tropical Disease.Journal of fungi (Basel, Switzerland) · 2022Review
- Fungal Keratitis: Clinical Features, Risk Factors, Treatment, and Outcomes.Journal of fungi (Basel, Switzerland) · 2022Article
- Microbiological Profile of Ocular Infection: A Large Retrospective Study.Iranian journal of public health · 2022Article
- Diagnosing Fungal Keratitis and Simultaneously IdentifyingJournal of fungi (Basel, Switzerland) · 2022Article
- Dual Drug Loaded Lipid Nanocarrier Formulations for Topical Ocular Applications.International journal of nanomedicine · 2022Article
- Microbiological Profiles of Ocular Fungal Infection at an Ophthalmic Referral Hospital in Southern China: A Ten-Year Retrospective Study.Infection and drug resistance · 2022Article
- Fungal keratitis caused by Pseudallescheria boydii: clinical and mycological characteristics.Journal of ophthalmic inflammation and infection · 2021Article
- Eye Infections Caused by Filamentous Fungi: Spectrum and Antifungal Susceptibility of the Prevailing Agents in Germany.Journal of fungi (Basel, Switzerland) · 2021Article
- The Consequences of Our Changing Environment on Life Threatening and Debilitating Fungal Diseases in Humans.Journal of fungi (Basel, Switzerland) · 2021Review
- Mycotic Keratitis-A Global Threat from the Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2021Review
- Mycotic Keratitis in a Tertiary Hospital in Northeastern MalaysiaTurkish journal of ophthalmology · 2020Article
- A 10-Year Retrospective Clinical Analysis of Fungal Keratitis in a Portuguese Tertiary Centre.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- An Omics Approach to Diagnosing or Investigating Fungal Keratitis.International journal of molecular sciences · 2019Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the rise in cases of fungal keratitis in recent years, this study was performed to better elucidate the microbiological profile, risk factors, and surgical intervention rates of fungal keratitis at a tertiary referral center in the Southeastern USA.
findingsThis is a retrospective case series of fungal keratitis infections treated at Duke University Eye Center from January 1, 1998, to October 6, 2008. Of the 4651 culture-proven corneal ulcers identified, 63 (1.4 %) were positive for fungal keratitis with a total of 69 fungal organisms isolated. The majority of isolates were filamentous species (44 of 69, 64 %), and the most commonly isolated organism was Curvularia (11 of 69, 16 %). Bacterial coinfections were found in 24 of the 63 cases (38 %). The most commonly associated risk factors were contact lens wear (n = 15, 24 %) and prior penetrating keratoplasty (PKP) (n = 15, 24 %). Twenty-three cases (37 %) required surgical intervention. The rate of surgical intervention was highest in patients with prior PKP (7/15, 47 %).
conclusionsIn this study, the leading risk factors for fungal keratitis were contact lens wear and prior PKP. Filamentous species were the most common causative pathogens. A relatively high rate of mixed bacterial-fungal infections was found. Patients with prior PKP were more likely to require surgery than patients without history of keratoplasties.
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