ArticleJournal of experimental botany2016
Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 103 citations in OpenAlex.
- Weaponizing nutrition: plants use a double strategy to fight herbivory, converting nutritionally essential fatty acids into defensive oxylipin signals.The New phytologist · 2026Article
- Branch architecture and flowering time are separately regulated by GhFL and GhSP2 in cotton.The Plant journal : for cell and molecular biology · 2026Article
- Identification of Genes Involved in Resistance to Flavescence Dorée Disease of Grapevine: A Model Study Using Arabidopsis thaliana.Molecular plant pathology · 2026Article
- Transcriptomic and physiological analyses reveal the molecular mechanisms underlying resistance to Cercospora beticola Sacc. (Cercospora leaf spot) in sugar beet.BMC plant biology · 2026Article
- A Reactive Antagonist Strategy: Cysteine-Directed Covalent Molecular Glue in Plant Hormone Receptor Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Tea Plant miR5368-p5 Negatively Regulates Resistance Against Lasiodiplodia theobromae Through Targeting the CsWRKY57-CsLRR-RLK Module.Molecular plant pathology · 2025Article
- Genome-Wide Identification of the TIFY Family inInternational journal of molecular sciences · 2025Article
- CsJAZ11 positively regulates tea plant resistance to Colletotrichum camelliae via transient silencing and overexpression.Plant cell reports · 2025Article
- Transcriptome Analysis Reveals the Molecular Mechanisms of Carrot Adaptation to Alternaria Leaf Blight.International journal of molecular sciences · 2024Article
- Genome-wide analysis of the potato GRF gene family and their expression profiles in response to hormone and Ralstonia solanacearum infection.Genes & genomics · 2024Article
- Genomic insights into local adaptation of upland cotton in China and Pakistan.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genome-wide identification and expression analysis of the Eriobotrya japonica TIFY gene family reveals its functional diversity under abiotic stress conditions.BMC genomics · 2024Article
- Pan-Genome Analysis ofInternational journal of molecular sciences · 2023Article
- Nitric Oxide and Globin Glb1 RegulateAntioxidants (Basel, Switzerland) · 2023Article
- Review
- Combined Transcriptomic and Metabolomic Analysis Reveals Insights into Resistance of ArabidopsisPlants (Basel, Switzerland) · 2022Article
- The Arabidopsis thaliana-Fusarium oxysporum strain 5176 pathosystem: an overview.Journal of experimental botany · 2022Review
- Genome-wide identification and characterization of the TIFY gene family in kiwifruit.BMC genomics · 2022Article
- Salicylic Acid in Root Growth and Development.International journal of molecular sciences · 2022Review
- NtbHLH49, a jasmonate-regulated transcription factor, negatively regulates tobacco responses toFrontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
Abstract
In Arabidopsis, jasmonate (JA)-signaling plays a key role in mediating Fusarium oxysporum disease outcome. However, the roles of JASMONATE ZIM-domain (JAZ) proteins that repress JA-signaling have not been characterized in host resistance or susceptibility to this pathogen. Here, we found most JAZ genes are induced following F. oxysporum challenge, and screening T-DNA insertion lines in Arabidopsis JAZ family members identified a highly disease-susceptible JAZ7 mutant (jaz7-1D). This mutant exhibited constitutive JAZ7 expression and conferred increased JA-sensitivity, suggesting activation of JA-signaling. Unlike jaz7 loss-of-function alleles, jaz7-1D also had enhanced JA-responsive gene expression, altered development and increased susceptibility to the bacterial pathogen PstDC3000 that also disrupts host JA-responses. We also demonstrate that JAZ7 interacts with transcription factors functioning as activators (MYC3, MYC4) or repressors (JAM1) of JA-signaling and contains a functional EAR repressor motif mediating transcriptional repression via the co-repressor TOPLESS (TPL). We propose through direct TPL recruitment, in wild-type plants JAZ7 functions as a repressor within the JA-response network and that in jaz7-1D plants, misregulated ectopic JAZ7 expression hyper-activates JA-signaling in part by disturbing finely-tuned COI1-JAZ-TPL-TF complexes.
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