Evidence map›Paper›PMID 26896845›Full record

ArticleDatabase : the journal of biological databases and curation2016

The UniProtKB guide to the human proteome.

Lionel Breuza, Sylvain Poux, Anne Estreicher, Maria Livia Famiglietti, Michele Magrane, Michael Tognolli, Alan Bridge, Delphine Baratin, Nicole Redaschi, UniProt Consortium

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed.

  1. Isolation of synovial fluid exosomes using phospholipid molecular imprinting technology and discovery of early diagnostic markers for osteoarthritis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
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  6. Review
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  8. Article
  9. Article
  10. Phytochemicals fromMicroorganisms · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. A web portal for exploring kinase-substrate interactions.NPJ systems biology and applications · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lionel BreuzaSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland lionel.breuza@isb-sib.ch.
Sylvain PouxSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
Anne EstreicherSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
Maria Livia FamigliettiSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
Michele MagraneEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Michael TognolliSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
Alan BridgeSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
Delphine BaratinSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
Nicole RedaschiSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel Servet, Geneva 4, 1211, Switzerland.
UniProt Consortium

Funding

UniProt: A centralized protein sequence and function resourceU41HG007822 · NHGRI · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI BATEMAN, ALEX · 2014 to 2017
$21.9M
British Heart Foundation SP/07/007/23671NHGRI NIH HHS 5U41HG007822-02NHGRI NIH HHS U41 HG007822
6 · The paper itself

Abstract

Advances in high-throughput and advanced technologies allow researchers to routinely perform whole genome and proteome analysis. For this purpose, they need high-quality resources providing comprehensive gene and protein sets for their organisms of interest. Using the example of the human proteome, we will describe the content of a complete proteome in the UniProt Knowledgebase (UniProtKB). We will show how manual expert curation of UniProtKB/Swiss-Prot is complemented by expert-driven automatic annotation to build a comprehensive, high-quality and traceable resource. We will also illustrate how the complexity of the human proteome is captured and structured in UniProtKB. Database URL: www.uniprot.org.

Indexed as

Databases, ProteinAutomationGenomeHumansKnowledge BasesPhenotypeProtein Processing, Post-TranslationalProteinsProteomeProteomicsRNA EditingSoftwareProteinsProteome

Identifiers

PMID26896845
PMCPMC4761109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.