Evidence map›Paper›PMID 26896263›Full record

Trial reportIndian heart journal

Angioplasty of unprotected left main coronary stenosis: Real world experience of a single-operator group from eastern India.

Shuvanan Ray, Alok Mazumder, Soumitra Kumar, Prithwiraj Bhattacharjee, David Rozario, Siddhartha Bandyopadhyay, Sanjeev S Mukherjee, P K Deb, Amal Bandyopadhyay

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shuvanan RayChief of Cardiac Intervention, Fortis Hospital, Anandapur, Kolkata, India. Electronic address: shuvananray@gmail.com.
Alok MazumderHead of the Department of Cardiology, B.R. Singh Hospital, Kolkata, India.
Soumitra KumarVisiting Consultant of Cardiology, Fortis Hospital, Anandapur, Kolkata, India.
Prithwiraj BhattacharjeeAssociate Consultant of Cardiology, Fortis Hospital, Anandapur, Kolkata, India.
David RozarioConsultant Interventional Cardiologist, Fortis Hospital, Anandapur, Kolkata, India.
Siddhartha BandyopadhyayConsultant Interventional Cardiologist, Fortis Hospital, Anandapur, Kolkata, India.
Sanjeev S MukherjeeConsultant Interventional Cardiologist, Fortis Hospital, Anandapur, Kolkata, India.
P K DebProfessor and Ex Head of the Department of Cardiology, ESI Hospital Maniktala, Kolkata, India.
Amal BandyopadhyayEx Consultant Cardiologist, I.P.G.M.E.&R. & S.S.K.M. Hospital, Kolkata, India.
Fortis Hospital · INEmployees' State Insurance Model Hospital · INMedical College and Hospital, Kolkata · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery bypass graft surgery is the standard treatment of unprotected left main coronary stenosis (ULMCA). However, in the real world scenario, many of these patients are unfit for CABG or prefer angioplasty as an alternative when offered the choice.

methodsA total of 86 clinically stable patients with ULMCA stenosis who were unfit or unwilling for CABG underwent PCI with DES at two tertiary care centers in Kolkata. Patients were followed up prospectively for a median of 34.6 months for major adverse cardiovascular events. Angiographic follow-up was done after 1 year of index procedure or earlier, if indicated.

resultsFifty-five patients (64%) had distal left main stenosis. Two-stent technique was used in 19 patients (22%) and single-stent technique in 36 patients (42%) with distal left main lesion. Thirteen patients (15.1%) had left ventricular ejection fraction (LVEF) of ≤45%. There was no in-hospital death, MI, or stent thrombosis. During follow-up, major adverse cardiac event (MACE) occurred in 9 patients (10.5%). Our study revealed significantly greater MACE in patients with distal left main lesion with LVEF ≤45% (50% vs 6.38%, p=0.0002), high SYNTAX score (36.36% vs 6.82%, p=0.008), and diabetes (17.95% vs 0.00%, p=0.07). Overall, also patients with Diabetes, LVEF ≤ 45%, and SYNTAX score >32 had significantly higher MACE. Use of IC Stent, IVUS, or procedural strategy in distal lesion did not affect MACE.

conclusionIn selective patients with low-intermediate SYNTAX score and without diabetes and LV dysfunction, ULMCA PCI with DES is feasible.

Indexed as

Drug-Eluting StentsPercutaneous Coronary InterventionRegistriesRisk AssessmentAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary StenosisCoronary VesselsFemaleFollow-Up StudiesHumansIndiaKaplan-Meier EstimateMaleMiddle AgedDrug eluting stentsPercutaneous coronary interventionUnprotected left main coronary artery

Identifiers

PMID26896263
PMCPMC4759495
OpenAlexW2285712819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.