ArticleApplied and environmental microbiology2016
Identifying Potential Mechanisms Enabling Acidophily in the Ammonia-Oxidizing Archaeon "Candidatus Nitrosotalea devanaterra".
Article in Applied and environmental microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 155 citations in OpenAlex.
- Soil Microbiome of Tropical Seasonal and Permanent Small Wetlands.Environmental microbiology reports · 2026Article
- Seasonal and Source-Associated Microbiome Dynamics in Brazilian Drinking Water.Microbial ecology · 2026Article
- The potential of plant-derived triterpenoids as biological nitrification inhibitors.Applied microbiology and biotechnology · 2026Article
- A novel North Sea ammonia-oxidizing archaeon Nitrosarchaeum marinum leverages a high abundance of transport systems to grow over a wide salinity range.FEMS microbiology ecology · 2026Article
- Ammonia oxidizers offset acidification stress via adaptive substrate affinity in aquatic ecosystems.Nature communications · 2026Article
- Hypothesizing the Biotherapeutic Potential of Nitrosotalea devanaterra: Targeting Ammonia Dependency to Disrupt Helicobacter pylori Survival Strategies in Gastritis.The Eurasian journal of medicine · 2026Article
- Elevated temperature simulating heatwaves restructures active nitrifying communities and associated viruses in tidal flats and agricultural soils.The ISME journal · 2026Article
- Acidotolerant soil nitrite oxidizer "ISME communications · 2026Article
- Evidence of biological nitrification inhibition in barley to support sustainable nitrogen management.Sustainable microbiology · 2026Article
- Microbial ecology of acidic, biogenic gypsum: community structure and distribution of extremophiles on freshly formed and relict sulfate deposits in a hydrogen sulfide-rich cave.Applied and environmental microbiology · 2025Article
- The Ammonia Oxidising Archaeon Nitrosopumilus maritimus Does Not Alter Iodine Oxidation State in Oxic Seawater.Environmental microbiology reports · 2025Article
- Acid tolerance and metabolic potential of comammox and nitrite-oxidizingISME communications · 2025Article
- Differential Responses of Soil Ammonia-oxidizing Bacterial and Archaeal Communities to Land-use Changes in Zambia.Microbes and environments · 2025Article
- Enrichment and identification of a moderately acidophilic nitrite-oxidizing bacterium.Water research X · 2025Article
- Adaptive traits ofmBio · 2024Article
- The Effects of MixedMicroorganisms · 2024Article
- Uranium Biogeochemistry in the Rhizosphere of a Contaminated Wetland.Environmental science & technology · 2024Article
- Transcriptional activity of ammonia oxidisers in response to soil temperature, moisture and nitrogen amendment.Frontiers in microbiology · 2024Article
- Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.ISME communications · 2024Article
- Assessing the activity of different plant-derived molecules and potential biological nitrification inhibitors on a range of soil ammonia- and nitrite-oxidizing strains.Applied and environmental microbiology · 2023Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ammonia oxidation is the first and rate-limiting step in nitrification and is dominated by two distinct groups of microorganisms in soil: ammonia-oxidizing archaea (AOA) and ammonia-oxidizing bacteria (AOB). AOA are often more abundant than AOB and dominate activity in acid soils. The mechanism of ammonia oxidation under acidic conditions has been a long-standing paradox. While high rates of ammonia oxidation are frequently measured in acid soils, cultivated ammonia oxidizers grew only at near-neutral pH when grown in standard laboratory culture. Although a number of mechanisms have been demonstrated to enable neutrophilic AOB growth at low pH in the laboratory, these have not been demonstrated in soil, and the recent cultivation of the obligately acidophilic ammonia oxidizer "Candidatus Nitrosotalea devanaterra" provides a more parsimonious explanation for the observed high rates of activity. Analysis of the sequenced genome, transcriptional activity, and lipid content of "Ca Nitrosotalea devanaterra" reveals that previously proposed mechanisms used by AOB for growth at low pH are not essential for archaeal ammonia oxidation in acidic environments. Instead, the genome indicates that "Ca Nitrosotalea devanaterra" contains genes encoding both a predicted high-affinity substrate acquisition system and potential pH homeostasis mechanisms absent in neutrophilic AOA. Analysis of mRNA revealed that candidate genes encoding the proposed homeostasis mechanisms were all expressed during acidophilic growth, and lipid profiling by high-performance liquid chromatography-mass spectrometry (HPLC-MS) demonstrated that the membrane lipids of "Ca Nitrosotalea devanaterra" were not dominated by crenarchaeol, as found in neutrophilic AOA. This study for the first time describes a genome of an obligately acidophilic ammonia oxidizer and identifies potential mechanisms enabling this unique phenotype for future biochemical characterization.
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