ArticleJournal of racial and ethnic health disparities2016
Racial Differences in Chronic Pain and Quality of Life among Adolescents and Young Adults with Moderate or Severe Hemophilia.
Article in Journal of racial and ethnic health disparities, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Social vulnerability, access to care, and outcomes in hemophilia.Blood vessels, thrombosis & hemostasis · 2026Article
- Development of a predictive model based on ultrasonographic features of brucella-associated periarthritis of the shoulder.Frontiers in cellular and infection microbiology · 2026Article
- Modelling US health equity impacts of emicizumab for severe haemophilia A: aggregate distributional cost-effectiveness analysis.BMJ open · 2025Article
- Assessment of Clinical Characteristics and Sociocontextual Factors on Medication Adherence in Children and Adolescents With Hemophilia.Pediatric blood & cancer · 2025Article
- Emerging Therapies in Hemophilia: Improving Equitable Access to Care.Journal of blood medicine · 2025Review
- Biobehavioral Predictors of Pain Intensity, Pain Interference, and Chronic Pain Episodes: A Prospective Cohort Study of African-American Adults.The journal of pain · 2024Article
- Racial and Ethnic Differences in Distress, Depression, and Quality of Life in people with hemophilia.Journal of racial and ethnic health disparities · 2024Article
- Bad blood: inequity in hemophilia care.Research and practice in thrombosis and haemostasis · 2024Article
- Adversity type and timing predict temporal summation of pain in African-American adults.Journal of behavioral medicine · 2023Article
- Race, ethnicity, and immune tolerance induction in hemophilia A in the United States.Research and practice in thrombosis and haemostasis · 2023Article
- Defining the Impact of Social Drivers on Health Outcomes for People with Inherited Bleeding Disorders.Journal of clinical medicine · 2022Review
- Health Equity Among Black Women in the United States.Journal of women's health (2002) · 2021Article
- Quality of Life of Latino and Non-Latino Youth With Sickle Cell Disease as Reported by Parents and Youth.Hispanic health care international : the official journal of the National Association of Hispanic Nurses · 2020Article
- Categorizing factors of adherence to parenteral treatment in growth hormone deficiencies and hemophilia: What should be the targets for future research?Patient preference and adherence · 2018Review
- Predictors of quality of life among adolescents and young adults with a bleeding disorder.Health and quality of life outcomes · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveWe explored racial differences in adherence to recommended clotting factor treatment regimens, chronic pain, and quality of life (QoL) among adolescents and young adults (AYAs) diagnosed with moderate or severe hemophilia.
methodsA convenience sample of hemophilia patients aged 13-25 years completed an online cross-sectional survey in 2012. Chronic pain was measured using the revised Faces Pain Scale (FPS-R) and dichotomized as high (FPS-R ≥ 4) or low (FPS-R < 4). QoL was measured with the SF-36.
resultsOf 80 AYA participants (79 male), most had severe disease (91 %) and hemophilia A (91 %). Most were white (76 %) and non-Hispanic (88 %). At the univariate level, compared to whites, non-whites were more likely to have produced an inhibitor against clotting factor treatment (74 vs 38 %, p < .01), less likely to have commercial health insurance (16 vs 63 %, p < .001), more likely to report high levels of chronic pain (FPS-R ≥ 4) (63 vs 26 %, p < .01), and had lower SF-36 physical composite summary (PCS) scores. Adjusted logistic and quantile regression modeling, respectively, revealed that non-whites were 5.31 (95 % CI 1.62, 17.4; p < .01) times more likely to report high chronic pain and had median PCS scores that were 26.0 (95 % CI 11.0, 40.9; p < .01) points lower than whites.
conclusionsTargeted efforts to prevent and manage chronic pain among non-white AYAs with moderate or severe hemophilia are necessary. After accounting for demographic and clinical differences, there were no racial differences in adherence to recommended clotting factor treatment regimens; however, non-whites were more than five times more likely to report high levels of chronic pain, which predicted worse overall physical QoL, bodily pain, physical and social functioning, and greater role limitations due to physical health.
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