Evidence map›Paper›PMID 26896039›Full record

ArticleLung2016

Admission Glucose Level Predicts In-hospital Mortality in Patients with Acute Pulmonary Embolism Who Were Treated with Thrombolytic Therapy.

Mehmet Bozbay, Huseyin Uyarel, Sahin Avsar, Ahmet Oz, Muhammed Keskin, Ahmet Murat, Adnan Kaya, Halil Atas, Ahmet Altug Cincin, Murat Ugur and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Lung, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Mehmet BozbayDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey. mbozbay42@gmail.com.
Huseyin UyarelDepartment of Cardiology, School of Medicine, Bezm-i Alem Vakif University, Istanbul, Turkey.
Sahin AvsarDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Ahmet OzDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Muhammed KeskinDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Ahmet MuratDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Adnan KayaDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Halil AtasDepartment of Cardiology, School of Medicine, Marmara University, Istanbul, Turkey.
Ahmet Altug CincinDepartment of Cardiology, School of Medicine, Marmara University, Istanbul, Turkey.
Murat UgurDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Mehmet ErenDepartment of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Tıbbiye Caddesi No: 13 Kadikoy, 34668, Istanbul, Turkey.
Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi · TRMarmara University · TRBezmiâlem Vakıf Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElevated admission serum glucose level is associated with unfavourable clinical outcomes in various clinical conditions. The aim of this study was to investigate the relationship between admission glucose levels and in-hospital and long-term adverse clinical outcomes in patients with pulmonary embolism (PE) treated with thrombolytic therapy.

methodsA total of 183 consecutive confirmed acute PE patients (98 female and 85 male; mean age 61.9 ± 15.7 years) who were treated with thrombolytic therapy enrolled in this study. The study population was categorised into four quartiles according to admission serum glucose levels (group I: glucose ≤115 mg/dl; group II: glucose >115-141 mg/dl; group III: glucose >141-195 mg/dl; and group IV: glucose ≥196 mg/dl).

resultsIn-hospital mortality was significantly higher in group IV (28.8 %) compared to group III (15.2 %), group II (6.6 %), and group I (2.1 %) (p < 0.001). In multivariate analysis, admission glucose level (OR 1.013, 95 % CI 1.004-1.021, p = 0.004) and admission anaemia (OR 0.602, 95 % CI 0.380-0.955, p = 0.03) were independent predictors of in-hospital mortality. The mean follow-up period was 34 months. During long-term follow-up, all-cause mortality, recurrent PE, major and minor bleeding were similar among the four groups.

conclusionAdmission glucose level is a simple, inexpensive, easily available, and effective laboratory parameter for predicting in-hospital mortality in patients with PE.

Indexed as

Hospital MortalityPatient AdmissionAgedBiomarkersBlood GlucoseChi-Square DistributionFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPredictive Value of TestsPulmonary EmbolismBiomarkersBlood GlucoseClinical outcomesGlucoseMortalityPulmonary embolismThrombolytic therapy

Identifiers

PMID26896039
OpenAlexW2286778046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.