Evidence map›Paper›PMID 26895920›Full record

Trial reportSurgical endoscopy2016

Effects of intraoperative protective lung ventilation on postoperative pulmonary complications in patients with laparoscopic surgery: prospective, randomized and controlled trial.

S J Park, B G Kim, A H Oh, S H Han, H S Han, J H Ryu

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03256396 (Intraoperative Positive End-Expiratory Pressure Setting Guided By Esophageal Pressure Measurement in Patients Undergoing Laparoscopic Gynecologic Surgery), which is not on this map. Cited by 34 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 9 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03256396 nacompletednot on this mapstarted 2018, after this paper: background citation

Intraoperative Positive End-Expiratory Pressure Setting Guided By Esophageal Pressure Measurement in Patients Undergoing Laparoscopic Gynecologic Surgery

TypeinterventionalSponsorMahidol UniversityRan2018 to 2018Enrolled44ConditionsPositive-Pressure Respiration/Methods, Esophagus/Physiopathology, Pleura/Physiopathology, Gynecologic Surgical ProceduresArmsPEEP setting based on esophageal pressure measured
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 9 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

S J ParkDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Gumiro-Gil 173, Bundang-gu, Seong-Nam Si, Seoul, 13620, South Korea.
B G KimDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Gumiro-Gil 173, Bundang-gu, Seong-Nam Si, Seoul, 13620, South Korea.
A H OhDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Gumiro-Gil 173, Bundang-gu, Seong-Nam Si, Seoul, 13620, South Korea.
S H HanDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Gumiro-Gil 173, Bundang-gu, Seong-Nam Si, Seoul, 13620, South Korea.
H S HanDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam-Si, Gyeonggi-do, South Korea.
J H RyuDepartment of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Gumiro-Gil 173, Bundang-gu, Seong-Nam Si, Seoul, 13620, South Korea. jinaryu@lycos.co.kr.
Seoul National University Bundang Hospital · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory functions are usually impaired during pneumoperitoneum for laparoscopic surgery. This randomized, controlled and single-blinded study was performed to evaluate whether intraoperative protective lung ventilation influences postoperative pulmonary complications after laparoscopic hepatobiliary surgery.

methodsSixty-two patients were randomized to receive either conventional ventilation with alveolar recruitment maneuver (tidal volume of 10 ml/kg with inspiratory pressure of 40 cmH2O for 30 s after the end of pneumoperitoneum, group R), or protective lung ventilation (low tidal volume of 6 ml/kg with positive end-expiratory pressure [PEEP] of 5 cmH2O, group P). Induction and maintenance of anesthesia were done with balanced anesthesia. Respiratory complications such as atelectasis, pneumonia or desaturation were observed postoperatively. The length of hospital stay, arterial blood gas analysis, peak inspiratory pressure and hemodynamic variables were also recorded. Results are presented as mean ± SD or number of patients (%).

resultsPostoperative pulmonary complications (P = 0.023) and desaturation below 90 % (P = 0.016) occurred less frequently in group P than in group R. Eight patients of group R and 3 patients of group P showed atelectasis. Pneumonia was diagnosed in 1 patient of group R. No differences were observed in the length of hospital stay, arterial blood gas analysis (pH, PaO2, PaCO2 and PAO2) and hemodynamic variables except PAO2, AaDO2 and peak inspiratory pressure between the two groups.

conclusionProtective lung ventilation (low tidal volume with PEEP) during pneumoperitoneum was associated with less incidences of pulmonary complications than conventional ventilation with alveolar recruitment maneuver after laparoscopic hepatobiliary surgery.

Indexed as

AdultAgedBlood Gas AnalysisDigestive System Surgical ProceduresFemaleHemodynamicsHumansHypoxiaIncidenceLaparoscopyLength of StayMaleMiddle AgedPneumoniaPneumoperitoneum, ArtificialPositive-Pressure RespirationAlveolar recruitment maneuverLaparoscopic surgeryPneumoperitoneumProtective lung ventilationPulmonary complication

Identifiers

PMID26895920
OpenAlexW2282782058

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.